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| | FLONICAMID Basic information |
| Product Name: | FLONICAMID | | Synonyms: | N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide;flonicamid (bsi, pa iso);iki-220;FLONICAMID STANDARD;flonicamid、flunicotamid;3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-;Aria;F 1785 | | CAS: | 158062-67-0 | | MF: | C9H6F3N3O | | MW: | 229.16 | | EINECS: | 203-887-8 | | Product Categories: | | | Mol File: | 158062-67-0.mol |  |
| | FLONICAMID Chemical Properties |
| Melting point | 157.5° | | Boiling point | 406.6±45.0 °C(Predicted) | | density | 1.377±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly, Heated) | | pka | 10.99±0.46(Predicted) | | form | neat | | color | Light Beige to Beige | | LogP | 0.840 (est) | | EPA Substance Registry System | Flonicamid (158062-67-0) |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 2 | | HS Code | 29333990 | | Hazardous Substances Data | 158062-67-0(Hazardous Substances Data) | | Toxicity | LD50 in male, female rats (mg/kg): 884, 1768 orally; in rats (mg/kg): >5000 dermally; in rats (mg/m3): >4900 by inhalation; LC50 in carp, rainbow trout (mg/l): >100, >91.9 (Morita) |
| | FLONICAMID Usage And Synthesis |
| Description | Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD50 = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture. | | Uses | Flonicamid is an novel insecticide with rapid inhibitory effect against aphid feeding. | | Uses | Insecticide. | | Uses | Flonicamid is a novel insecticide with rapid inhibitory effect against aphid feeding. Useful in cannabis testing kits as a component of pesticide mixes (P698240). | | Definition | ChEBI: A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom. | | Application | With foliar spray application at the rates of 50-100 g a.i./ha, onicamid
exhibits excellent aphicidal activity and also shows good insecticidal
activity against other sucking insect pests such as thrips, white ies,
planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees,
cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid
soil applications also provide control of the foliar pests mentioned above. | | Definition | Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was assessed through laboratory selection and determining inheritance pattern and cross-resistance potential to five insecticides in house fly, Musca domestica L. Very low to high flonicamid resistance in M. domestica populations was found compared with the susceptible strain (SS). | | Mode of action | Flonicamid rapidly inhibits the feeding behavior of aphids, and has
better action through ingestion than by contact.
Its mode of action is different from other insecticides such as neonicotinoids, pymetrozine and pyri uquinazon.
Flonicamid belongs to IRAC Group 29 and is the only insecticide in this
class. |
| | FLONICAMID Preparation Products And Raw materials |
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