ERYTHROMYCIN B

ERYTHROMYCIN B Basic information
Product Name:ERYTHROMYCIN B
Synonyms:ERYTHROMYCIN B (150 MG);12-deoxy-erythromyci;12-deoxyerythromycin;abbot24091;berythromycin;Erythromycin B (100 mg);12-DeoxyerythroMycin, BerythroMycin;Erythromycin B/3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hex
CAS:527-75-3
MF:C37H67NO12
MW:717.93
EINECS:
Product Categories:
Mol File:527-75-3.mol
ERYTHROMYCIN B Structure
ERYTHROMYCIN B Chemical Properties
Melting point 191-195 °C
Boiling point 807.6±65.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly, Heated)
form neat
pka13.49±0.70(Predicted)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
HS Code 2941500000
MSDS Information
ERYTHROMYCIN B Usage And Synthesis
UsesErythromycin B is a co-metabolite of Erythromycin A (E649950), an antibacterial agent.
UsesErythromycin B (12-deoxyerythromycin A) is a minor co-metabolite of erythromycin produced Saccharopolyspora erythreae. Erythromycin B exhibits broad spectrum antibiotic activity, albeit less potent than erythromycin A. Erythromycin B played an integral part of the SAR studies of semi-synthetic erythromycins, however none reached clinical development.
DefinitionChEBI: Erythromycin B is an erythromycin that consists of erythronolide B having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is functionally related to an erythronolide B.
ERYTHROMYCIN B Preparation Products And Raw materials
erythronolide B 13-O,1-Seco-11-deoxy-1,11-epoxyerythromycin ERYTHROMYCIN OXIME 16-Hydroxyerythromycin Erythromycin ethylsuccinate Erythromycin A Enol Ether (9S)-9-Amino-9-deoxoerythromycin 3,6-di(4-pyridinyl)-1,4-dihydro-1,2,4,5-tetraazine Erythromycin EP Impurity L Erythromycin A Oxime Erythromycin Impurity 9 (9Z)-ErythroMycin A OxiMe 3,6-DI-4-PYRIDYL-1,2,4,5-TETRAZINE ANHYDROERYTHROMYCIN A ErythroMycin A 9,11-IMino Ether ERYTHROMYCIN PROPIONATE 13-Desethyl-13-propyl-Erythromycin A Erythromycin Impurity

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