ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates 2-(4-NITROPHENYL)BUTYRIC ACID

2-(4-NITROPHENYL)BUTYRIC ACID

2-(4-NITROPHENYL)BUTYRIC ACID Basic information
Product Name:2-(4-NITROPHENYL)BUTYRIC ACID
Synonyms:2-(p-nitrophenyl)-butyricaci;2-(p-nitrophenyl)butyricacid;alpha-ethyl-4-nitro-benzeneaceticaci;alpha-ethyl-4-nitrobenzeneaceticacid;ALPHA-ETHYL-4-NITROPHENYLACETIC ACID;A-ETHYL-4-NITROBENZONIC ACID;2-(4-NITROPHENYL)BUTYRIC ACID;α-(p-Nitro-phenyl)butyric acid
CAS:7463-53-8
MF:C10H11NO4
MW:209.2
EINECS:231-256-3
Product Categories:
Mol File:7463-53-8.mol
2-(4-NITROPHENYL)BUTYRIC ACID Structure
2-(4-NITROPHENYL)BUTYRIC ACID Chemical Properties
Melting point 122-123 °C
Boiling point 371.2±25.0 °C(Predicted)
density 1.287±0.06 g/cm3(Predicted)
pka3.91±0.10(Predicted)
Safety Information
MSDS Information
2-(4-NITROPHENYL)BUTYRIC ACID Usage And Synthesis
Uses2-(4-Nitrophenyl)butyric acid is a key intermediate in the synthesis of indobufen, a new generation of anti-platelet aggregation agents.
SynthesisSynthesis of 2-(4-nitrophenyl)butyric acid, using α-phenylbutyronitrile as the starting material, to produce 2-(4-nitrophenyl)butyronitrile by nitration reaction, and then by hydrolysis reaction to produce 2-(4-nitrophenyl)butyric acid.
2-(4-NITROPHENYL)BUTYRIC ACID Preparation Products And Raw materials
Raw materialsMethanol-->Sulfuric acid-->Dichloromethane-->Acetic acid-->Nitric acid-->Bromoethane-->Benzeneacetonitrile-->2-Phenylbutyric acid
3,3-DIMETHYL-7-NITRO-1-OXO-ISOCHROMAN-4-CARBOXYLIC ACID 3-(2-HYDROXY-1,3-THIAZOL-5-YL)-2-(4-NITROPHENYL)PROPANOIC ACID AKOS BBS-00000226 1-(4-NITROPHENYL)CYCLOPENTANE-1-CARBOXYLICACID 2-(4-NITRO-PHENYL)-3-OXO-3-(2,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER 2-(4-NITROPHENYL)PENTANOIC ACID DIMETHYL 2-ALLYL-2-(2,4-DINITROPHENYL)MALONATE DIMETHYL 2-(3-CHLOROBENZYL)-2-(4-NITROPHENYL)MALONATE 3-(3-CHLOROPHENYL)-2-(4-NITROPHENYL)PROPANOIC ACID SALOR-INT L100293-1EA 2-DIETHYLAMINOETHYL 1-(4-NITROPHENYL)CYCLOPENTANECARBOXYLATE HYDROCHLORIDE DIMETHYL 2-[(2-CHLORO-1,3-THIAZOL-5-YL)METHYL]-2-(4-NITROPHENYL)MALONATE 4-NITROPHENYLSUCCINIC ACID DIMETHYL 2-ETHYL-2-(4-NITROPHENYL)MALONATE DIMETHYL 2-(4-METHYLBENZYL)-2-(4-NITROPHENYL)MALONATE DIMETHYL 2-[(2-CHLORO-1,3-THIAZOL-5-YL)METHYL]-2-(2,4-DINITROPHENYL)MALONATE DIMETHYL 2-ALLYL-2-(4-NITROPHENYL)MALONATE DIMETHYL 2-(4-NITROPHENYL)-2-PROPYLMALONATE
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