ChemicalBook Product Catalog Organic Chemistry Nitrogen Compounds S(-)-RACLOPRIDE L-TARTRATE

S(-)-RACLOPRIDE L-TARTRATE

S(-)-RACLOPRIDE L-TARTRATE Basic information
Product Name:S(-)-RACLOPRIDE L-TARTRATE
Synonyms:(S)-3,5-dichloro-N-((1-ethylpyrrolidin -2-yl)methyl)-2-hydroxy-6- methoxybenzamide (2R,3R) -2,3-dihydroxysuccinate;(2S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)-METHYL]-6- METHOXYSALICYLAMIDE;BENZAMIDE, 3,5-DICHLORO-N-[[(2S)-1-ETHYL-2-PYRROLIDINYL]METHYL]-2-HYDROXY-6-METHOXY-;3,5-Dichloro-N-[(2S)-1-ethyl-2-pyrrolidinyl]-2-hydroxy-6-methoxybenzamide;FLA-870;RAC;3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-6-hydroxybenzamide;3,5-Dichloro-N-[[(2S)-1-ethylpyrrolidine-2α-yl]methyl]2-hydroxy-6-methoxybenzamide
CAS:84225-95-6
MF:C15H20Cl2N2O3
MW:347.24
EINECS:
Product Categories:Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Dopamine receptor
Mol File:84225-95-6.mol
S(-)-RACLOPRIDE L-TARTRATE Structure
S(-)-RACLOPRIDE L-TARTRATE Chemical Properties
Melting point 52.0 to 56.0 °C
Boiling point 420.3±45.0 °C(Predicted)
density 1.288±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility H2O: 89 mg/mL
pka5.93±0.50(Predicted)
form solid
color white
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS CV3465000
HS Code 2933.99.8290
MSDS Information
ProviderLanguage
SigmaAldrich English
S(-)-RACLOPRIDE L-TARTRATE Usage And Synthesis
DescriptionRaclopride is a selective dopamine D2/D3 receptor antagonist with Ki values of 1.8, 3.5, 2,400, and 18,000 nM for D2, D3, D4, and D1 receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.
Chemical PropertiesYellowish solid
UsesA labelled dopamine receptor
Usesneuroleptic;selective dopamine D1/D2 receptors antagonist
UsesRaclopride is a potent D2DR/D3DR antagonist.
DefinitionChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.
Biological ActivitySelective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .
storageStore at -20°C
S(-)-RACLOPRIDE L-TARTRATE Preparation Products And Raw materials
Loratadine Cisapride 3,5-DICHLOROSALICYLALDEHYDE Diclometide BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-6-METHOXY-, (S)- 3,5-DICHLORO-2-HYDROXYBENZYLAMINE (S)-RACLOPRIDE, [METHOXY-3H] (S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIHYDROXY-BENZAMIDE N-(3-CHLOROBENZYL)BUTAN-1-AMINE 2,4-Dichloro-5-methoxyphenol S(-)RACLOPRIDE L-TARTRATE >97% SELECTIVE D2 DOPAMINE N1-BENZYL-N2,N2-DIETHYL-1,2-PROPANEDIAMINE N-(5-CHLORO-2-METHOXYBENZYL)-N-METHYLAMINE 4-Chlororesorcinol N-(5-chloro-2-methoxybenzyl)-N-ethylamine 4,6-DICHLORORESORCINOL S(-)-RACLOPRIDE L-TARTRATE Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:)
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