[LEU5]-ENKEPHALIN

[LEU5]-ENKEPHALIN Basic information
Product Name:[LEU5]-ENKEPHALIN
Synonyms:[Leu5]-Enkephalin,Tyr-Gly-Gly-Phe-Leu,YGGFL,ICI-114740,Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin?, BR;leucine enkephalin acetate hydrate;(5-LEUCINE)ENKEPHALIN 96+%;L-Tyr-Gly-Gly-L-Phe-L-Leu-OH;Tyr-Gly-Gly-Phe-Leu-OH;Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu;L-TYR-GLY-GLY-PHE-LEU;LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE)
CAS:58822-25-6
MF:C28H37N5O7
MW:555.62
EINECS:261-457-1
Product Categories:Pepetides;peptides;Peptide;Opioid receptor and opioid-like receptor;58822-25-6
Mol File:58822-25-6.mol
[LEU5]-ENKEPHALIN Structure
[LEU5]-ENKEPHALIN Chemical Properties
Melting point 130-133 °C
alpha +32.3°(c=9,メタノール)
Boiling point 998.8±65.0 °C(Predicted)
density 1.274±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility ≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO
pka3.40±0.10(Predicted)
form Lyophilized powder
Water Solubility Soluble in water (1 mg/ml ).
Safety Information
Safety Statements 22-24/25
WGK Germany 3
3-10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
[LEU5]-ENKEPHALIN Usage And Synthesis
UsesEndogenous opioid neurotransmitter/neuromodulator that is an agonist at ? and δ opioid receptors, localization in brain parallels the localization of δ receptors.
DefinitionChEBI: Leu-enkephalin is a pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. It has a role as a delta-opioid receptor agonist, a mu-opioid receptor agonist, a neurotransmitter, an analgesic, a human metabolite and a rat metabolite. It is functionally related to a L-tyrosine, a glycine, a L-phenylalanine and a L-leucine. It is a tautomer of a Leu-enkephalin zwitterion.
storageStore at -20°C
[LEU5]-ENKEPHALIN Preparation Products And Raw materials
ICI 174,864 [ALA2,LEU5]-ENKEPHALIN ALA-ALA-ALA-TYR-GLY-GLY-PHE-LEU LEUCINE ENKEPHALIN ACETATE SALT (3,5-DIBROMO-TYR1)-LEU-ENKEPHALIN (D-ALA2,D-LEU5)-ENKEPHALIN AMIDE [D-SER2, LEU5]-ENKEPHALIN-THR ALPHA-CASEIN (90-95) D-ALA2-LEU5-ENKEPHALIN BOC-LEU-ENKEPHALIN N-ALPHA-T-BOC-[LEU5]-ENKEPHALIN LEU-ENKEPHALIN (SULFATED) [D-Ser2,Leu5]enkephalin methyl ester PEPTIDE E ENKEPHALIN-LEU, [3,5-3H] [LEU5]-ENKEPHALIN AMIDE ([125I]-TYR)-LEU-ENKEPHALIN [LEU5]-ENKEPHALIN

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