4-(Trifluoromethyl)benzyl alcohol

4-(Trifluoromethyl)benzyl alcohol Basic information
Product Name:4-(Trifluoromethyl)benzyl alcohol
Synonyms:Benzenemethanol, 4-(trifluoromethyl)-;RARECHEM AL BD 0111;PTF-BYL;P-(TRIFLUOROMETHYL)BENZYL ALCOHOL;4-(TRIFLUOROMETHYL)BENZYL ALCOHOL;4-TRIFLUOROMETHYL BENZENE METHANOL;[4-(TRIFLUOROMETHYL)PHENYL]METHANOL;4-(trifluoromethyl)benzylic alcohol
CAS:349-95-1
MF:C8H7F3O
MW:176.14
EINECS:206-494-6
Product Categories:Benzhydrols, Benzyl & Special Alcohols;Alcohol;Alcohols;Fluorine Compounds;C7 to C8;Oxygen Compounds
Mol File:349-95-1.mol
4-(Trifluoromethyl)benzyl alcohol Structure
4-(Trifluoromethyl)benzyl alcohol Chemical Properties
Melting point 22-25 °C
Boiling point 78-80 °C/4 mmHg (lit.)
density 1.286 g/mL at 25 °C (lit.)
refractive index n20/D 1.459(lit.)
Fp 213 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Liquid After Melting
pka13.91±0.10(Predicted)
Specific Gravity1.286
color Clear colorless to light brown
Water Solubility Soluble in water.
BRN 1450174
CAS DataBase Reference349-95-1(CAS DataBase Reference)
NIST Chemistry Reference4-(Trifluoromethyl)benzyl alcohol(349-95-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
10-23
Hazard Note Irritant
HazardClass CORROSIVE
HS Code 29062900
MSDS Information
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4-(Trifluoromethyl)benzyl alcohol Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
Uses4-(Trifluoromethyl)benzyl alcohol, is used as a pharmaceutical intermediate, it is also used to predict the NMR spectrum. 4-(Trifluoromethyl)benzyl alcohol is employed as a reagent in, for example, kinetic studies of phosphonoformate prodrugs and aquachromium(IV).
DefinitionChEBI: 4-(trifluoromethyl)benzyl alcohol is an aromatic primary alcohol. It is functionally related to a benzyl alcohol.
Synthesis Reference(s)Tetrahedron Letters, 29, p. 4057, 1988 DOI: 10.1016/S0040-4039(00)80416-5
General DescriptionPhotocatalytic oxidation of 4-(trifluoromethyl)benzyl alcohol to corresponding aldehydes on TiO2 photocatalyst under O2 atmosphere has been reported.
4-(Trifluoromethyl)benzyl alcohol Preparation Products And Raw materials
Preparation Products4-TRIFLUOROMETHYLBENZYLSULFONYL CHLORIDE-->4-Trifluoromethylbenzyl chloride-->Benzenesulfonamide, N-[[4-(trifluoromethyl)phenyl]methyl]- -->4-(Trifluoromethyl)benzoic acid
5-METHYL-2-(TRIFLUOROMETHYL)BENZYL ALCOHOL ALPHA-METHYL-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL,ALPHA-METHYL-M-(TRIFLUOROMETHYL)BENZYL ALCOHOL 5-CHLORO-2-(TRIFLUOROMETHYL)BENZYL ALCOHOL A-METHYL-2-(TRIFLUOROMETHYL)BENZYL ALCOHOL 3-(Trifluoromethyl)benzyl alcohol p-morpholino-alpha-(trifluoromethyl)benzyl alcohol 2,3,5,6-TETRAFLUORO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL 4-FLUORO-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL 3-BROMO-5-(TRIFLUOROMETHYL)BENZYL ALCOHOL (r)-(-)-α-(trifluoromethyl)benzyl alcohol,(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Trifluoromethyl 4-Trifluoromethylsalicylic acid 4-METHOXY-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL Benzyl 4-METHYL-2-(TRIFLUOROMETHYL)BENZYL ALCOHOL -METHYL-2-TRIFLUOROMETHYLBENZYL ALCOHOL ALPHA-METHYL-O-(TRIFLUOROMETHYL)BENZYL ALCOHOL,ALPHA-METHYL-2-(TRIFLUOROMETHYL)BENZYL ALCOHOL ETHYL 4-(TRIFLUOROMETHYL)BENZOATE

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