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| | TRIMETHYLACETIC ANHYDRIDE Basic information |
| Product Name: | TRIMETHYLACETIC ANHYDRIDE | | Synonyms: | 2,2-DIMETHYLPROPIONIC ANHYDRIDE;2,2-Dimethylpropionic anhydride, Pivalic anhydride;Bis(2,2-dimethylpropionic acid)anhydride;Bis(pivalic acid)anhydride;Dipivalic anhydride;Trimethylacetic anhydride,99%;Propanoic acid, 2,2-dimethyl-, anhydride;Propanoicacid,2,2-dimethyl-,anhydride | | CAS: | 1538-75-6 | | MF: | C10H18O3 | | MW: | 186.25 | | EINECS: | 216-263-1 | | Product Categories: | Aliphatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aliphatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 1538-75-6.mol |  |
| | TRIMETHYLACETIC ANHYDRIDE Chemical Properties |
| Boiling point | 193 °C(lit.) | | density | 0.918 g/mL at 25 °C(lit.) | | vapor pressure | 62.1Pa at 25℃ | | refractive index | n20/D 1.409(lit.) | | Fp | 135 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Miscible with acetonitrile. | | form | Liquid | | color | Clear colorless | | Sensitive | Moisture Sensitive | | BRN | 386552 | | LogP | 2.15 | | CAS DataBase Reference | 1538-75-6(CAS DataBase Reference) | | EPA Substance Registry System | Propanoic acid, 2,2-dimethyl-, anhydride (1538-75-6) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2920 8/PG 2 | | WGK Germany | 3 | | F | 9-13-21 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29159000 |
| | TRIMETHYLACETIC ANHYDRIDE Usage And Synthesis |
| Chemical Properties | clear colourless liquid | | Uses | Trimethylacetic anhydride was used:
- in solid-phase oligonucleotide synthesis
- in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
- as acylation and esterification reagent for anilines
- as acylation and esterification reagent for phenols
| | Uses | A metabolite of a double prodrug (6-dGCV-DPiv | | Flammability and Explosibility | Notclassified |
| | TRIMETHYLACETIC ANHYDRIDE Preparation Products And Raw materials |
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