Sodium glycolate

Sodium glycolate Basic information
Product Name:Sodium glycolate
Synonyms:Acetic acid, 2-hydroxy-, sodium salt (1:1);HYDROXYACETIC ACID SODIUM SALT;GLYCOLIC ACID SODIUM SALT;Sodiumglycollate;sodiumlycolate;SODIUM GLYCOLATE;SODIUM HYDROXYACETATE;Aceticacid,hydroxy-,monosodiumsalt
CAS:2836-32-0
MF:C2H3NaO3
MW:98.03
EINECS:220-624-9
Product Categories:Pharmaceutical Intermediates
Mol File:2836-32-0.mol
Sodium glycolate Structure
Sodium glycolate Chemical Properties
Melting point 210-218℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Powder
color White to off-white
Water Solubility Soluble
LogP-1.046 (est)
CAS DataBase Reference2836-32-0(CAS DataBase Reference)
EPA Substance Registry SystemSodium glycolate (2836-32-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-26
RTECS MC5525000
TSCA Yes
HS Code 29189900
Toxicitycat,LDLo,intravenous,1gm/kg (1000mg/kg),BEHAVIORAL: MUSCLE WEAKNESSBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: ATAXIA,Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 306, 1942.
MSDS Information
ProviderLanguage
ACROS English
ALFA English
Sodium glycolate Usage And Synthesis
Chemical PropertiesWhite to off-white powder
UsesBuffer in electrodeless plating and textile fin- ishing.
UsesSodium glycolate is used as a disintegrant, suspending agent, gelling agent, buffering agent and in pharmaceutical grade for tablets and capsules. Further, it is used in cosmetics and personal care products primarily as an exfoliant, as pH adjusters, skin-conditioning agents and as a flavoring agent.
DefinitionChEBI: An organic sodium salt comprising equal numbers of sodium and glycolate ions.
Purification MethodsPrecipitate it from aqueous solution by adding EtOH and dry it in air. Also recrystallise it from H2O, where its solubility is 38% at 0o and 61% at100o. [Beilstein 3 III 370, 3 IV 573.]
Sodium glycolate Preparation Products And Raw materials
Raw materialsChloroacetic acid
Preparation ProductsButyl hydroxyacetate
Glycolic acid Diphacinone-Na Ethanol DL-Mandelic acid Sodium diacetate Sodium dehydroacetate 2-Hydroxyphenylacetic acid Chlorophyllin Diclofenac sodium Sodium α-naphthyl acetate COBALT GLUCONATE Zinc gluconate Disodium edetate dihydrate Sodium formate Sodium citrate Sodium chlorate Sodium bicarbonate Sodium gluconate

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