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| 1,2,3,4-Tetrahydrocarbazole Basic information |
Product Name: | 1,2,3,4-Tetrahydrocarbazole | Synonyms: | ,3,4,9-Tetrahydro-1H-carbazole;1H-Indole, 2,3-(1,4-butanediyl)-;2,3,4,9-tetrahydro-1h-carbazol;2,3-Tetramethylene-1H-indole;5,6,7,8-tetrahydro-carbazol;5,6,7,8-Tetrahydrocarbazole;Carbazole, 1,2,3,4-tetrahydro-;Carbazole, 5,6,7,8-tetrahydro- | CAS: | 942-01-8 | MF: | C12H13N | MW: | 171.24 | EINECS: | 213-385-7 | Product Categories: | Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Building Blocks;Carbazoles;Heterocyclic Building Blocks | Mol File: | 942-01-8.mol | |
| 1,2,3,4-Tetrahydrocarbazole Chemical Properties |
Melting point | 118-120 °C (lit.) | Boiling point | 325-330 °C (lit.) | density | 1.1459 (rough estimate) | refractive index | 1.6544 (estimate) | Fp | 325-330°C | storage temp. | Sealed in dry,Room Temperature | pka | 17.84±0.20(Predicted) | form | powder to crystal | color | White to Orange to Green | Water Solubility | Insoluble in water. Solubility in methanol (almost transparency). | BRN | 133771 | CAS DataBase Reference | 942-01-8(CAS DataBase Reference) | NIST Chemistry Reference | 1H-Carbazole, 2,3,4,9-tetrahydro-(942-01-8) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-37/39 | WGK Germany | 2 | RTECS | FE6300000 | HS Code | 29339900 |
| 1,2,3,4-Tetrahydrocarbazole Usage And Synthesis |
Chemical Properties | beige crystalline powder | Uses | 1,2,3,4-Tetrahydrocarbazole can be used as a starting material to prepare:
- Spiro[cyclopentane-1,2′-indolin-3′-one] by photooxygenation.
- 9-Acyl-1,2,3,4-tetrahydrocarbazoles by N-acylation reactions.
- Carbazole via palladium-catalyzed asymmetric hydrogenation reaction.
| Uses | It finds its application as a pharmaceutical intermediate and in the synthesis of aspidospermidine alkaloids. | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 14, p. 934, 1966 DOI: 10.1248/cpb.14.934 Tetrahedron Letters, 26, p. 161, 1985 DOI: 10.1016/S0040-4039(00)61869-5 |
| 1,2,3,4-Tetrahydrocarbazole Preparation Products And Raw materials |
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