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CROCONAZOLE

CROCONAZOLE Basic information
Product Name:CROCONAZOLE
Synonyms:CROCONAZOLE;CLOCONAZOLE;1-[1-[2-[(3-Chlorophenyl)methoxy]phenyl]ethenyl]-1H-imidazole;710674-S;Pilzcin;1-(1H-Imidazole-1-yl)-1-[2-(3-chlorobenzyloxy)phenyl]ethene;1-[1-[2-(3-Chlorobenzyloxy)phenyl]vinyl]-1H-imidazole;1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]ethenyl]-1H-imidazole
CAS:77175-51-0
MF:C18H15ClN2O
MW:310.78
EINECS:
Product Categories:
Mol File:77175-51-0.mol
CROCONAZOLE Structure
CROCONAZOLE Chemical Properties
Melting point 72-73℃
Boiling point 501.5±60.0 °C(Predicted)
density 1.16
storage temp. 2-8°C
pka6.29±0.10(Predicted)
Safety Information
MSDS Information
CROCONAZOLE Usage And Synthesis
UsesCloconazole is an antifungal azole drug.
DefinitionChEBI: Croconazole is an imidazole antifungal drug, a conazole antifungal drug, a member of monochlorobenzenes and an aromatic ether.
Metabolic pathwayWhen male rabbits are administered croconazole by intravenous injection, as many as 16 metabolites are excreted in the urine and 13 metabolites are identified. The biotransformation reaction of croconazole includes ring hydroxylation, O-dechlorobenzylation, and the loss of the imidazole ring.
CROCONAZOLE Preparation Products And Raw materials
Raw materialsSodium hydride-->Benzyl bromide-->Croconazole hydrochloride
CROCONAZOLE HYDROCHLORIDE 1-(1-2-HYDROXYPHENYL)ETHENYL)-1H-IMIDAZOLE 2-BENZYLOXYBENZYLAMINE CROCONAZOLE
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