OXONIC ACID POTASSIUM SALT

OXONIC ACID POTASSIUM SALT Basic information
Product Name:OXONIC ACID POTASSIUM SALT
Synonyms:1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt;5-azaoroticacid,potassiumsalt;4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt, Allantoxanic acid;(OXO)Oteracil potassium;Potassium 4,6-dioxo-1H-1,3,5-triazine-2-carboxylate;Potassium s-triazine-2,4-dione-6-carboxylate;1,4,5,6-Tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid potassium salt;Allantoxanic acid potassium
CAS:2207-75-2
MF:C4H2KN3O4
MW:195.17
EINECS:218-627-5
Product Categories:Anti-cancer&immunity;oncology;Classes of Metal Compounds;K (Potassium) Compounds (excluding simple potassium salts);Typical Metal Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Anticancer
Mol File:2207-75-2.mol
OXONIC ACID POTASSIUM SALT Structure
OXONIC ACID POTASSIUM SALT Chemical Properties
Melting point 300 °C(lit.)
storage temp. Inert atmosphere,2-8°C
solubility Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
form Powder
color White
Water Solubility Soluble in hot water.
CAS DataBase Reference2207-75-2(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS RR4580000
HS Code 29349990
MSDS Information
OXONIC ACID POTASSIUM SALT Usage And Synthesis
DescriptionOxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; ), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats. Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas.
Chemical PropertiesOff-White Solid
UsesAntitumor effect potentiator and antitumor agent
UsesOxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.
UsesOxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.
DefinitionChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity.
OXONIC ACID POTASSIUM SALT Preparation Products And Raw materials
Raw materials3-OXALURIC ACID-->1-(2,5-Dioxo-2,5-dihydro-1H-imidazol-4-yl)urea-->Allantoin
Potassium methoxide Potassium iodide Potassium acetate hydrate 5-AZAURACIL S 1 (combination) 1,2,3-Propanetricarboxylicacid,2-hydroxy-,potassiumsalt HYDANTOIC ACID Oxonic Acid Potassium lactate Potassium sodium tartrate Potassium perchlorate Potassium Acetate DIOXOPROMETHAZINE HCL Potassium chloride 1,3,5-Triazine Potassium RESMETHRIN OXONIC ACID POTASSIUM SALT

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