ChemicalBook Product Catalog Organic Chemistry Hydrocarbons and derivatives Cyclic hydrocarbons 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Basic information
Product Name:1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
Synonyms:CYCLOBUTANECARBONITRILE, 1-(4-CHLOROPHENYL);CYCLOBUTANECARBONITRILE, 1-(4-CHLOROPHENYL)(INTERMEDIATE OF SIBUTRAMINE);1-CYANO-1-(4-CHLOROPHENYL)CYCLOBUTANE;1-(4-CHLOROPHENYL)-1-CYCLOBUTANECARBONITRILE;1-(4-CHLOROPHENYL)CYCLOBUTANECARBONITRILE;NSC 154613;SIBU-1;Sibutramine Impurity F
CAS:28049-61-8
MF:C11H10ClN
MW:191.66
EINECS:248-799-7
Product Categories:Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;C10 to C27;Cyanides/Nitriles;Nitrogen Compounds
Mol File:28049-61-8.mol
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Structure
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Chemical Properties
Boiling point 295 °C (lit.)
density 1.137 g/mL at 25 °C (lit.)
refractive index n20/D 1.548(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
color Clear Colourless to Pale Yellow
CAS DataBase Reference28049-61-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 36-36/37/39-26
RIDADR UN3276
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 29269095
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Usage And Synthesis
Chemical PropertiesColourless Oil
UsesAn intermediate in the preparation of Sibutramine and respective metabolites
Uses1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile (1-(4-chlorophenyl)-1-cyanocyclobutane) can be used in the synthesis of pharmacologically active metabolites of the anti-obesity drug-sibutramine.
General Description1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile is also referred as 1-(4-chlorophenyl)-1-cyanocyclobutane.
1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile Preparation Products And Raw materials
Cyclopropane 2-ETHOXYSPIRO[3.5]NONANE-1,1-DICARBONITRILE 1-Chloro-2-methylpropane Chlorodimethylphenylsilane 3-OXO-CYCLOBUTANECARBONITRILE 2-Chloro-3-cyanopyridine 3,3,4,4-TETRAMETHOXYCYCLOBUTANE-1,2-DICARBONITRILE 2-Chloro-2-methylpropane 2,2,3,3-TETRAMETHOXY-4-METHYLCYCLOBUTANE-1,1-DICARBONITRILE 3-Methylenecyclobutanecarbonitrile 1-(3,4-DICHLOROPHENYL)CYCLOBUTANECARBONITRILE 1-Chlorobutane TRANS-CYCLOBUTANE-1,2-DICARBONITRILE 1-CYANO-2,2,3,3-TETRAFLUOROCYCLOBUTANE CHLOROPHENYLSILANE 97 Triphenylmethyl Chloride 1-(2-cyano-1,3,4,4a,5,6,7,8b-octahydrocyclobuta[a]naphthalen-2a(2H)-yl)-1-methylpyrrolidinium 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
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