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| | 1,2-Dichlorobenzene Basic information |
| Product Name: | 1,2-Dichlorobenzene | | Synonyms: | 1,2-Dichlorobenzene, 99+%, for HPLC;1,2-DICHLOROBENZENE EMSURE 2,5 L;1,2-DICHLOROBENZENE FOR SYNTHESIS;1,2-DICHLOROBENZENE EMSURE 1 L;NSC 60644;1,2-Dichlorobenzene, Anhydrous, SeptuM-Sealed Bottle, DriSolv(R);1.2-DICHLOROBENZENE HPLC/SPECTRO;1,2-Dichlorobenzene, SuperDry, J&KSeal | | CAS: | 95-50-1 | | MF: | C6H4Cl2 | | MW: | 147 | | EINECS: | 202-425-9 | | Product Categories: | Anhydrous Solvents;Solvent Bottles;Organics;Solvent by Application;Solvent Packaging Options;Sure/Seal Bottles;Analytical Chemistry;Standard Solution of Volatile Organic Compounds for Water & Soil Analysis;Standard Solutions (VOC);Amber Glass Bottles;CHROMASOLV for HPLCSolvents;CHROMASOLV Solvents (HPLC, LC-MS);CHROMASOLV(R) HPLC Grade Solvents;Solvent Bottles;Intermediates of Dyes and Pigments;Alpha Sort;Alphabetic;DIA - DIC;Carbon Steel Cans with NPT Threads;ReagentPlus(R) Solvent Grade Products;ReagentPlus(R)Semi-Bulk Solvents;ReagentPlus(R)Solvents;ACS and Reagent Grade Solvents;Amber Glass Bottles;Carbon Steel Cans with NPT Threads;ReagentPlus;ReagentPlus Solvent Grade Products;Semi-Bulk Solvents;alkyl chloride;Pesticides intermediate;DIA - DICAnalytical Standards;Alphabetical Listings;D;DAlphabetic;NMR Reference Standards;NMRStable Isotopes;Spectroscopy;Stable Isotopes;DIA - DICPesticides&Metabolites;Herbicides;Others;Volatiles/ Semivolatiles;Pesticides&Metabolites;Spectrophotometric Grade Solvents;Spectrophotometric GradeSolvents;Anhydrous Grade SolventsSolvents;Solvents;Sure/Seal? Bottles;K00001 | | Mol File: | 95-50-1.mol |  |
| | 1,2-Dichlorobenzene Chemical Properties |
| Melting point | -15 °C | | Boiling point | 179 °C | | density | 1.306 g/mL at 25 °C(lit.) | | vapor density | 5.1 (vs air) | | vapor pressure | 1.2 mm Hg ( 20 °C) | | refractive index | n20/D 1.551 | | Fp | 150 °F | | storage temp. | Store below +30°C. | | solubility | 0.13g/l | | form | Liquid | | color | Clear colorless to very slightly yellow | | Odor | Aromatic; characteristic aromatic. | | explosive limit | 2.2-12%(V) | | Water Solubility | 0.13 g/L (20 ºC) | | λmax | λ: 296 nm Amax: 1.00
λ: 300 nm Amax: 0.30
λ: 305 nm Amax: 0.20
λ: 335 nm Amax: 0.05
λ: 375-400 nm Amax: 0.01 | | Merck | 14,3056 | | BRN | 606078 | | Henry's Law Constant | 1.92 at 25 °C (gas stripping-GC, Shiu and Mackay, 1997) | | Exposure limits | Ceiling 50 ppm (～300 mg/m3) (MSHA,
OSHA, and NIOSH); IDLH 1700 ppm
(NIOSH). | | Stability: | Stable, but possibly light sensitive. Combustible. Incompatible with oxidizing agents, aluminium, aluminium alloys. Attacks some rubbers and plastics. | | LogP | 3.433 at 25℃ | | CAS DataBase Reference | 95-50-1(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1,2-dichloro-(95-50-1) | | IARC | 3 (Vol. Sup 7, 73) 1999 | | EPA Substance Registry System | o-Dichlorobenzene (95-50-1) |
| | 1,2-Dichlorobenzene Usage And Synthesis |
| Chemical Properties | 1,2-Dichlorobenzene (DCB, o-Dichlorobenzene, ODB, Orthodichlorobenzene),
C6H4Cl2, is a colorless to pale yellow liquid with a pleasant aromatic odor. It is a
combustible liquid and can form explosive mixtures with air at or above 151°F.
Combustion and thermal decomposition products include hydrogen chloride gas,
phosgene and chloro-carbons. Its flammable (explosive) limits are as follows:
Lower 2.2%, Upper 9.2%.
| | Physical properties | Clear, colorless to pale yellow liquid with a pleasant, aromatic, grassy or vegetable-type odor. At
40 °C, the lowest concentration at which an odor was detected was 200 μg/L. At 25 °C, the lowest
concentration at which a taste was detected was 200 μg/L (Young et al., 1996). A detection odor
threshold concentration of 4.2 mg/m3 (699 ppbv) was reported by Punter (1983). | | Uses | Solvent for waxes, gums, resins, tars, rubbers, oils, asphalts; insecticide for termites and locust borers; fumigant; deodorizer; removing sulfur from illuminating gas; as degreasing agent for metals, leather, wool; as ingredient of metal polishes; as heat transfer medium; as intermediate in the manufacture of dyes. | | Uses | 1,2-Dichlorobenzene is used as a solvent; asa fumigant; as an insecticide for termites;as a degreasing agent for metals, wool, andleather; and as a heat transfer medium. | | Production Methods | 1,2-Dichlorobenzene is produced by reacting liquid benzene with gaseous chlorine in the presence of a catalyst at moderate temperature and atmospheric pressure.
Dichlorobenzenes are primarily produced by the chlorination of benzene in the presence of a catalyst (FeCl3 or AlCl3) although there are other possible synthetic routes. The two commercially important isomers are the ortho- and para-dichlorobenzenes. | | Definition | ChEBI: 1,2-dichlorobenzene is a dichlorobenzene carrying chloro substituents at positions 1 and 2. It has a role as a hepatotoxic agent and a metabolite. | | General Description | A clear colorless liquid with a pleasant odor. Denser than water and insoluble in water. Flash point 150°F. Toxic by inhalation and ingestion. Used to make other chemicals, solvents, fumigants and insecticides and for many other uses. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 1,2-Dichlorobenzene is sensitive to prolonged exposure to light. 1,2-Dichlorobenzene can react vigorously with oxidizers. 1,2-Dichlorobenzene is incompatible with aluminum and aluminum alloys. 1,2-Dichlorobenzene attacks some forms of plastics, rubber and coatings. . | | Health Hazard | 1,2-Dichlorobenzene exhibits low acute toxi city by inhalation, ingestion, and skin absorp tion. It is more toxic than chlorobenzene.The symptoms are lacrimation, depression ofcentral nervous system, anesthesia, and liverdamage. Lethal concentration in rats for a7-hour exposure period is in the range of800 ppm. The oral LD50 value in rabbits is500 mg/kg. There is no evidence of carcino genicity in animals. | | Fire Hazard | Special Hazards of Combustion Products: Poisonous vapors including hydrogen chloride gas, chlorocarbons, chlorine | | Flammability and Explosibility | Nonflammable | | Chemical Reactivity | Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. | | Safety Profile | Poison by ingestion and
intravenous routes. Moderately toxic by
inhalation and intraperitoneal routes. An
experimental teratogen. Other experimental
reproductive effects. An eye, skin, and
mucous membrane irritant. Causes liver and
hdney injury. Questionable carcinogen.
Mutation data reported. A pesticide.
Flammable when exposed to heat or flame.
Can react vigorously with oxidizing
materials. To fight fire, use water, foam,
CO2, or dry chemical. Slow reaction with
aluminum may lead to explosion during
storage in a sealed aluminum container. When heated to decomposition it emits
toxic fumes of Cl-. See also
CHLOROBENZENE and
CHLORINATED HYDROCARBONS,
AROMATIC. | | Potential Exposure | The major uses of o-DCB are as
a process solvent in the manufacturing of toluene diisocyanate and as an intermediate in the synthesis of dyestuffs,
herbicides, and degreasers. p-Dichlorbenzene is used
primarily as a moth repellant, a mildew control agent;
space deodorant; and in insecticides, which accounts for
90% of the total production of this isomer. Information is
not available concerning the production and use of m-DCB.
However, it may occur as a contaminant of o-or p-DCB
formulations. Both o-and p-isomers are produced almost
entirely as by-products during the production of
monochlorobenzene | | Purification Methods | Contaminants may include the p-isomer and trichlorobenzene [Suslick et al. J Am Chem Soc 106 4522 1984]. It should be shaken with conc or fuming H2SO4, washed with water, dried with CaCl2, and distilled from CaH2 or sodium in a glass-packed column. Low conductivity material (ca 10-10 mhos) has been obtained by refluxing with P2O5, fractionally distilling and passing it through a column packed with silica gel or activated alumina: it is stored in a dry-box under N2 or with activated alumina. [Beilstein 5 IV 654.] | | Incompatibilities | 1,2-Dichlorobenzene forms hydrogen chloride gas when in the presence of strong oxidizers or chemically active metals like aluminum, or when heated to decomposition (HSDB 2007). | | Waste Disposal | Incineration, preferably
after mixing with another combustible fuel. Care must be
exercised to assure complete combustion to prevent
the formation of phosgene. An acid scrubber is necessary
to remove the halo acids produced. Consult with
environmental regulatory agencies for guidance on
acceptable disposal practices. Generators of waste containing
this contaminant (≥100 kg/mo) must conform with EPA
regulations governing storage, transportation, treatment, and
waste disposal |
| | 1,2-Dichlorobenzene Preparation Products And Raw materials |
| Raw materials | Benzene-->Chlorine-->Copper(I) chloride-->2-Chloroaniline | | Preparation Products | 3,5-Dichloroaniline-->Norfloxacin-->METHYLISOCYANATE 1 X 500MG NEAT-->Coumarin 6-->Pigment Geen 7-->Butyl isocyanate-->3,4-Dichloroaniline-->3-Amino-5-methylisoxazole-->Mebendazole-->VAT BLACK 27-->3-Chloro-4-fluoroaniline-->Permanent Violet RL-->1,4-Dichlorobenzene-->DIRECT YELLOW 27-->2,6-Dichlorobenzonitrile-->3,4-Dichloronitrobenzene-->1,2,4,5-TETRACYANOBENZENE-->Acenaphthenequinone-->1,3-Dichloroisoquinoline-->4-(3-METHYL-UREIDO)-BENZENESULFONYL CHLORIDE-->1,2,4,5-BENZENETETRACARBOXAMIDE-->1-Naphthyl isocyanate-->N,N,N',N'-Tetraphenylbenzidine-->2,7-DIBROMO-9H-CARBAZOLE-->2,4,6-Trimethoxybenzaldehyde-->PYROMELLITIC DIIMIDE-->3，7-dichloro-8-dichloro methyl quinoline-->3，7-dichloro-8-chloro methyl quinoline-->2-NAPHTHYL ISOCYANATE-->4,5-Dichloro-1,2-benzenediamine-->3,4-Dichlorobenzophenone-->3,5-Dibromo-4-hydroxybenzaldehyde-->Pigment Red 176-->(3,4-Diaminophenyl)phenylmethanone-->tert-Butylisocyanate-->Acetofenate-->C. I. Pigment Yellow 173-->3,4-Dichlorobenzaldehyde-->DICHLORPHENAMIDE-->4,5-DICHLORO-BENZENE-1,3-DISULFONYLDICHLORIDE |
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