Epifluorohydrin

Epifluorohydrin Basic information

Product Name:	Epifluorohydrin
Synonyms:	(fluoromethyl)oxirane;1,2-epoxy-3-fluoro-propan;1-fluoro-2,3-epoxypropane;2-(Fluoromethyl)oxirane;3-Fluoropropene-1,2-oxide;Epifluorhydrine;Propane, 1,2-epoxy-3-fluoro-;3-Fluoro-1,2-propenoxide 99%
CAS:	503-09-3
MF:	C3H5FO
MW:	76.07
EINECS:	207-960-1
Product Categories:	Contact Printing;Fluorine-Containing Monomers for 157 nm UV Lithography Resist Polymers;Lithography Monomers;Self Assembly &;Building Blocks;Chemical Synthesis;Epoxides;Fluorinated Building Blocks;Heterocyclic Fluorinated Building Blocks;Materials Science;Micro/NanoElectronics;Organic Building Blocks;Other Fluorinated Heterocycles;Oxygen Compounds;monomer
Mol File:	503-09-3.mol

Epifluorohydrin Chemical Properties

Boiling point	85-86 °C (lit.)
density	1.067 g/mL at 25 °C (lit.)
refractive index	n20/D 1.368(lit.)
Fp	40 °F
storage temp.	0-6°C
form	liquid
color	clear
CAS DataBase Reference	503-09-3(CAS DataBase Reference)
NIST Chemistry Reference	Oxirane, (fluoromethyl)-(503-09-3)
EPA Substance Registry System	Epifluorohydrin (503-09-3)

Safety Information

Hazard Codes	F,T
Risk Statements	11-23/24/25-34
Safety Statements	16-26-45-38-36/37/39-33
RIDADR	UN 2924 3/PG 2
WGK Germany	3
RTECS	TZ3325000
Hazard Note	Flammable/Highly Toxic
HazardClass	6.1(a)
PackingGroup	I
HS Code	2910900090

MSDS Information

Provider	Language
Epifluorohydrin	English
SigmaAldrich	English
ACROS	English

Epifluorohydrin Usage And Synthesis

Chemical Properties	clear colourless liquid
Uses	Epifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.
General Description	Clear colorless liquid.
Air & Water Reactions	Highly flammable. Water soluble.
Reactivity Profile	A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.
Health Hazard	ACUTE/CHRONIC HAZARDS: Epifluorohydrin is a lacrimator. When heated to decomposition it emits toxic fumes.
Fire Hazard	Epifluorohydrin is flammable.

Epifluorohydrin Preparation Products And Raw materials

Raw materials	1,3-DIFLUORO-2-PROPANOL-->1-Propanol, 3-bromo-2-fluoro--->Diazene, 1,2-bis(1-methylethyl)-, (1E)--->Isopropyl hydroperoxide-->ALLYL FLUORIDE-->Epichlorohydrin-->Isopropyl alcohol-->Acetaldehyde-->Acetone-->1,3-Dichloro-2-propanol-->3-Chloro-1,2-propanediol
Preparation Products	Butanenitrile, 4-fluoro-3-hydroxy--->1-BROMO-3-FLUOROPROPAN-2-OL

(NONAFLUORO-N-BUTYL)EPOXIDE 1,1,1-TRIFLUORO-2,3-EPOXYPROPANE 4-Chloroperfluoro-(1,2-epoxy)butane 6H-PERFLUOROHEXYL-1,2-EPOXIDE 2,2-BIS(TRIFLUOROMETHYL)OXIRANE Hexafluoropropylene oxide Resin epoxy EPOXY 1,4-Bis(2',3'-epoxypropyl)perfluorobutane 1,1,1-TRIFLUORO-2,3-EPOXYBUTANE 2,2-DIFLUORO-3,3-BIS(TRIFLUOROMETHYL)OXIRANE R-(+)-2-TRIFLUOROMETHYLOXIRANE 2-BROMO-2-(TRIFLUOROMETHYL)DIFLUOROOXIRANE (1,1,2,2-TETRAFLUOROETHYL)TRIFLUOROOXIRANE Epichlorohydrin Epifluorohydrin CIS-2-BENZOYL-3-(TRIFLUOROMETHYL)OXIRANE Propylene oxide

Email:[email protected] [email protected]

Copyright © 2024 Mywellwork.com All rights reserved.