Cinepazide

Cinepazide Basic information
Product Name:Cinepazide
Synonyms:CINEPAZIDE;1-(pyrrolidin-1-ylcarbonylmethyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine;PIPERAZINE,1-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]-4-[1-OXO-3-(3,4,5-TRIMETHOXYPHENYL)-2-PROPENYL];1-(1-Pyrrolidinylcarbonylmethyl)-4-[3-(3,4,5-trimethoxyphenyl)acryloyl]piperazine;1-[(1-Pyrrolidinylcarbonyl)methyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]piperazine;2-Propen-1-one, 1-[4-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1-piperazinyl]-3-(3,4,5-trimethoxyphenyl)-;Cinepazide USP/EP/BP;Cinepazide free base
CAS:23887-46-9
MF:C22H31N3O5
MW:417.5
EINECS:245-928-9
Product Categories:
Mol File:23887-46-9.mol
Cinepazide Structure
Cinepazide Chemical Properties
Boiling point 637.8±55.0 °C(Predicted)
density 1.200±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka5.22±0.10(Predicted)
CAS DataBase Reference23887-46-9(CAS DataBase Reference)
Safety Information
MSDS Information
Cinepazide Usage And Synthesis
UsesCinepazide is an injection in the treatment of acute myocardial infarction and its effect on serum inflammatory factors.
DefinitionChEBI: Cinepazide is an olefinic compound. It is functionally related to a cinnamic acid.
World Health Organization (WHO)Cinepazide, a vasodilating agent, was first introduced into medicine in 1974. It is used in the treatment of peripheral and cerebral vascular disorders. Following reports of blood dyscrasias, including agranulocytosis and thrombocytopenia, associated with the use of the drug, the Spanish Committee on Drug Surveillance has recommended its withdrawal. In other countries, the approved product information of preparations containing cinepazide has been amended to include a relevant warning on these adverse effects.
Cinepazide Preparation Products And Raw materials
Raw materials3',4',5'-trimethoxycinnamoyl chloride-->1-((PYRROLIDINE-1-CARBONYL)METHYL)PIPERAZINE
1-[4-(2-AMINOETHYL)PIPERAZIN-1-YL]ETHANONE 1-(2-PYRROLIDINOETHYL)PIPERAZINE Octyl 4-methoxycinnamate CINEPAZIDE MALEATE Anisole 1-CINNAMOYL-PIPERAZINE Ethyl 4-methoxycinnamate (Trifluoromethoxy)benzene N,N-DIETHYL-2-PIPERAZIN-1-YL-ACETAMIDE Piperazine 1-((PYRROLIDINE-1-CARBONYL)METHYL)PIPERAZINE p-Anisic acid p-Anisidine 1-[3-(4-HYDROXY-3-METHOXYPHENYL)-OXO-2-PROPENYL]-PIPERAZINE p-Anisaldehyde Cintramide 4-Methoxycinnamic acid Cinepazide

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