ChemicalBook Product Catalog Organic Chemistry Organic fluorine compound Fluorotoluene series 4-Bromo-3-fluorotoluene

4-Bromo-3-fluorotoluene

4-Bromo-3-fluorotoluene Basic information
Product Name:4-Bromo-3-fluorotoluene
Synonyms:4-BROMO-3-FLUOROTOLUENE;3-FLUORO-4-BROMO-TOLUENE;4-Bromo-3-fluorotoluene,98+%;4-Bromo-3-fluorotoluene 98%;4-Bromo-3-fluoro-1-methylbenzene;4-Bromo-3-flurotoluene;3-FLUORO-4-BROMO-TOLUONE;4-BroMo-3-fluorotoluene, 98% 5GR
CAS:452-74-4
MF:C7H6BrF
MW:189.02
EINECS:629-423-4
Product Categories:Aryl;C7;Halogen toluene;Miscellaneous;Bromine Compounds;Halogenated Hydrocarbons;Fluorin-contained toluene series;blocks;Bromides;FluoroCompounds;Aromatic Halides (substituted);Fluorine Compounds
Mol File:452-74-4.mol
4-Bromo-3-fluorotoluene Structure
4-Bromo-3-fluorotoluene Chemical Properties
Boiling point 95 °C/50 mmHg (lit.)
density 1.494 g/mL at 25 °C (lit.)
refractive index n20/D 1.53(lit.)
Fp 95 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
Specific Gravity1.494
color Clear light yellow
BRN 2500154
CAS DataBase Reference452-74-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 10-36/37/38
Safety Statements 26-37/39-16
RIDADR UN 1993 3/PG 3
WGK Germany 3
Hazard Note Irritant
HazardClass 3
PackingGroup III
HS Code 29039990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-Bromo-3-fluorotoluene Usage And Synthesis
Chemical Propertiescolorless to light yellow liqui
Uses4-Bromo-3-fluorotoluene is used in the synthesis of S-trityl-L-cysteine based inhibitors that show potent antitumor activity in lung cancer models. Chemical reagent for organic synthesis.
Uses4-Bromo-3-fluorotoluene may be used in the preparation of 1-(4-cyano-3- fluorobenzyl)-5-imidazolecarboxaldehyde and 1-bromo-4-bromomethyl-2-fluorobenzene.
General Description4-Bromo-3-fluorotoluene (1-bromo-2-fluoro-4-methylbenzene) is an aryl fluorinated building block. Synthesis of 4-bromo-3-fluorotoluene from o-nitro-p-toluidine (Fast Red Base GL), via diazo reaction at high temperature, Sandmeyer reaction, reduction and Schiemann reaction has been reported. Its density and refractive index have been determined.
4-Bromo-3-fluorotoluene Preparation Products And Raw materials
Preparation Products2-Fluoro-4-methylphenylboronic acid-->2-Fluoro-4-methylaniline-->4-(BROMOMETHYL)-2-FLUOROBENZONITRILE-->5-BROMO-4-FLUORO-2-METHYLANILINE-->4-Bromo-5-fluoro-2-nitrotoluene-->tert-Butyl ((3-aminobenzo[d]isoxazol-6-yl)methyl)carbamate-->tert-butyl N-[(3-amino-1H-indazol-6-yl)methyl]carbamate
Tosufloxacin tosylate Benzotrifluoride 4-Bromo-3-fluorobenzotrifluoride Ethyl bromodifluoroacetate 4-Bromo-2,3,5,6-tetrafluorotoluene 4-BROMO-2-CHLORO-5-FLUOROBENZOYL CHLORIDE 4-BROMO-2,3,5,6-TETRAFLUOROBENZONITRILE 3-FLUORO-4-BROMO-ACETOPHENONE 3-Fluorobenzotrifluoride 4-Bromotoluene 4-Bromo-3-fluorobenzoic acid Bromine 4-BROMO-3'-FLUORO-4'-METHOXYBENZOPHENONE 4-BROMO-3-FLUORO-2'-METHOXYBENZOPHENONE 2-BROMO-3,5-DIMETHYLFLUOROBENZENE 4-BROMO-2,3,5,6-TETRAFLUOROBENZOTRIFLUORIDE 4-Bromo-3-fluorotoluene 2-Methylbenzotrifluoride
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