ChemicalBook Product Catalog Chemical Reagents Organic reagents Phosphonate / phosphonate DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID

DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID

DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID Basic information
Product Name:DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
Synonyms:(+/-)-AP-4;AP-4;DL-2-AMINO-4-PHOSPHONOBUTANOIC ACID;DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID;DL-AP4;(+/-)-2-AMINO-4-PHOSPHONOBUTYRIC ACID;ANTI-TFAP4 antibody produced in mouse;bHLHc41
CAS:20263-07-4
MF:C4H10NO5P
MW:183.1
EINECS:
Product Categories:Glutamate receptor;Glutamate
Mol File:20263-07-4.mol
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID Structure
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID Chemical Properties
Melting point 225 °C
storage temp. 0-6°C
form solid
color white
Water Solubility Soluble to 33 mM in water
BRN 2093908
CAS DataBase Reference20263-07-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
ProviderLanguage
ALFA English
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID Usage And Synthesis
Uses(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.
General Description(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.
Biological ActivityBroad spectrum EAA ligand. See separate isomers (D-(-)-2-Amino-4-phosphonobutyric acid and L-(+)-2-Amino-4-phosphonobutyric acid).
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID Preparation Products And Raw materials
Sodium Butyrate Napropamide (D,L)-(+,-)-2-Amino-4-(diethylphosphono)butanoic acid, ethyl ester, 98 % D-AP4 L-AP4 (S)-2-Amino-2-methyl-4-phosphonobutanoic acid 3-(ethoxycarbonyl)-3-aminopropylphosphonic acid (S)-MAP4 HYDROCHLORIDE (D,L)-(+/-)-2-AMINO-4-(DIETHYLPHOSPHONO)BUTANOIC ACID, ETHYL ESTER, HYDROCHLORIDE 4-PHOSPHONOBUTYRIC ACID [3H]-(L)-AP4 DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
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