2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL

2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Basic information
Product Name:2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL
Synonyms:2-(DI-TERT-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL;2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL;2-Di-t-butylphosphino-2'-methylbiphenyl,99%;PHOSPHINE, BIS(1,1-DIMETHYLETHYL)(2''-METHYL[1,1''-BIPHENYL]-2-YL)-;tBuMePhos;2-(Di-tert-butylphosphino)-2'-methyl- biphenyl, 98+%;2-(Di-tert-butylphosphino)-2'-methylbiphenyl ,99%;Di-tert-butyl(2'-Methylbiphenyl-2-yl)phosphine
CAS:255837-19-5
MF:C21H29P
MW:312.43
EINECS:607-748-2
Product Categories:Achiral Phosphine;Aryl Phosphine
Mol File:255837-19-5.mol
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Structure
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Chemical Properties
Melting point 91-93 °C
Boiling point 408.0±24.0 °C(Predicted)
storage temp. Inert atmosphere,Room Temperature
form Crystalline Powder
color White
Sensitive Air Sensitive
InChIInChI=1S/C21H29P/c1-16-12-8-9-13-17(16)18-14-10-11-15-19(18)22(20(2,3)4)21(5,6)7/h8-15H,1-7H3
InChIKeyUJONYAVMBYXBJQ-UHFFFAOYSA-N
SMILESP(C(C)(C)C)(C(C)(C)C)C1=CC=CC=C1C1=CC=CC=C1C
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26
WGK Germany 3
TSCA No
HS Code 29319090
MSDS Information
ProviderLanguage
ACROS English
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Usage And Synthesis
Description2-(Di-t-butylphosphino)-2'-methylbiphenyl is a phosphine that has two functional groups, amide and aromatic hydrocarbon. The geometric isomers of this molecule are cis and trans. It can be used to diagnose reactions in a reaction vessel with mammalian cells. It also reacts with pyrazoles, triazoles and other molecules to form isomers at the 2 position of the biphenyl ring.
Chemical PropertiesWhite crystalline powder
Usessuzuki reaction
UsesA ligand for the palladium-catalyzed monoarylation of malonate esters, 1,3-diketones and isolated nitroalkanes.
Application2-(Di-t-butylphosphino)-2'-methylbiphenyl has been shown to have cancer chemotherapeutic potential, as it inhibits the growth of cancer cells by binding to DNA and inhibiting its transcription. This compound also induces apoptosis in some cancer cells.
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Preparation Products And Raw materials
Raw materialsDi-tert-butylphosphine-->2-BroMo-2'-Methylbiphenyl-->Di-tert-butylchlorophosphane-->1,2-Dibromobenzene-->2-Tolylboronic acid
2-DI-TERT-BUTYLPHOSPHINO-3,4,5,6-TETRAM& 2-(Di-tert-butylphosphino)biphenyl 2-DI-TERT-BUTYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL DI-TERT-BUTYLPHENYLPHOSPHINE 2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL

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