Sitagliptin Impurity 1

Sitagliptin Impurity 1 Basic information
Product Name:Sitagliptin Impurity 1
Synonyms:1,2,4-Triazolo[4,3-a]pyrazine,7-[(3S)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-;Sitagliptin Impurity 1;Sitagliptin impurity 1/Sitagliptin EP Impurity A/Sitagliptin S-Isomer/(S)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine;Sitagliptin-13;Sitagliptin impurity SKY-8-ISO;1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3S)-;(S)-3-amino-4-(3,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one;Sitagliptin EP Impurity A(Free base)
CAS:823817-55-6
MF:C16H15F6N5O
MW:407.31
EINECS:
Product Categories:
Mol File:823817-55-6.mol
Sitagliptin Impurity 1 Structure
Sitagliptin Impurity 1 Chemical Properties
Boiling point 529.9±60.0 °C(Predicted)
density 1.61±0.1 g/cm3(Predicted)
pka7.20±0.10(Predicted)
Safety Information
MSDS Information
Sitagliptin Impurity 1 Usage And Synthesis
Sitagliptin Impurity 1 Preparation Products And Raw materials
Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Impurity 34 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin DeaMino IMpurity 1 Sitagliptin Impurity 14 (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione (S)-Duloxetine SuccinaMide Sitagliptin Defuoro IMpurity 3 Sitagliptin Impurity 27 N'-[(2Z)-Piperazin-2-ylidene]trifluoroacetohydrazide 4-[3-(Methylamino)-1-(2-thienyl)propyl]- Sitagliptin N-Phoshate IMpurity rac-Sitagliptin EP Impurity B HCl Sitagliptin impurity H HCl Sitagliptin Sitagliptin Impurity 28

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