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BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER

BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Basic information
Product Name:BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
Synonyms:BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER;METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE;N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER;(4R)-1-BOC-4-FLUORO-L-PROLINE METHYL ESTER;(2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylic acid O1-tert-butyl ester O2-methyl ester;(2S,4R)-N-Boc-trans-4-fluoro-L-proline methyl ester;N-Boc-trans-4-fluoro-L-proline methyl ester;1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
CAS:203866-18-6
MF:C11H18FNO4
MW:247.26
EINECS:
Product Categories:Asymmetric Synthesis;Building Blocks;Chemical Synthesis;Chiral Building Blocks;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Pyrrolidines
Mol File:203866-18-6.mol
BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Structure
BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Chemical Properties
Melting point 34-39 °C
density 1.16
Fp 110 °C
storage temp. 2-8°C
optical activity[α]22/D -80.0°, c = 1 in methanol
Water Solubility Insoluble in water.
Safety Information
WGK Germany 3
HS Code 2933998090
MSDS Information
BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Usage And Synthesis
UsesN-Boc-trans-4-fluoro-L-proline methyl ester is used to prepare (S)-2-[N-(N'-benzyl-(S)-4-fluoro-L-prolyl)amino]benzophenone by reacting with of 2-aminobenzophenone in the presence of potassium tert -butoxide.
BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER Preparation Products And Raw materials
Preparation Products(4R)-4-FLUORO-L-PROLINE HCL-->BOC-TRANS-4-FLUORO-L-PROLINE
(2S,3S)-1-(tert-butoxycarbonyl)-3-hydroxypiperidine-2-carboxylic acid BOC-TRANS-4-FLUORO-5-OXO-L-PROLINE METHYL ESTER (2R,4S)-N-Boc-trans-4-Fluoro-D-proline methyl ester BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER (2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid METHYL (2S,4R)-4-FLUOROPROLINATE BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
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