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Sacubitril Impurity

Sacubitril Impurity Basic information
Product Name:Sacubitril Impurity
Synonyms:1012341-48-8 enantioMer;(2E,4S)-5-[1,1-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid;2-Pentenoic acid, 5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-, (2E,4S)-;impurity 41;Sacubitril Impurity;(S,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid;Sacubitril Impurity 103
CAS:1015037-46-3
MF:C23H27NO4
MW:381.46
EINECS:
Product Categories:
Mol File:1015037-46-3.mol
Sacubitril Impurity Structure
Sacubitril Impurity Chemical Properties
Boiling point 595.6±50.0 °C(Predicted)
density 1.132±0.06 g/cm3(Predicted)
pka4.67±0.19(Predicted)
Safety Information
MSDS Information
Sacubitril Impurity Usage And Synthesis
Uses(2E,4S)-5-[1,1''-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid was used in the study to process for preparation of biaryl-substituted 4-aminobutyric acids by hydrogenation of the corresponding alkenoates.
Sacubitril Impurity Preparation Products And Raw materials
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Sacubitril Impurity 31 Sacubitril Impurity 10 Sacubitril Impurity 16 LCZ Impurity ahu377 isomer 2 (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride Sacubitril Impurity 13 Sacubitril Impurity 19 Sacubitril Impurity 14 Sacubitril Impurity 17 Sacubitril impurity 030 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Sacubitril Impurity 20 Sacubitril Impurity 15 LCZ696 InteMediate
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