(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Basic information
Product Name:(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
Synonyms:(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol;Fluconazole EP Impurity H;2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-bromopropan-2-ol;Fluconazole impurity H (EP);Fluconazole Impurity 8(Fluconazole EP Impurity H);1-bromo-2-(2,4-difluorophenyl)-3-(1,2,4-triazol-1-yl)propan-2-ol;1-bromo-2-(2,4-difluorophenyl);Fluconazole-8
CAS:150194-52-8
MF:C11H10BrF2N3O
MW:318.12
EINECS:
Product Categories:
Mol File:150194-52-8.mol
(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Structure
(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Chemical Properties
Melting point 116-117°C
Boiling point 446.4±55.0 °C(Predicted)
density 1?+-.0.1 g/cm3(Predicted)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka11.06±0.29(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Usage And Synthesis
Uses2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-bromopropan-2-ol (Fluconazole EP Impurity H) is an impurity of the antifungal agent Fluconazole (F421000).
(2RS)-1-bromo-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Preparation Products And Raw materials
Fluconazole FLUCONAZOLE RELATED COMPOUND B (10 MG) (2-(4-FLUOROPHENYL)-1,3-BIS(1 H-1,2,4-TRIAZOL-1 -YL)-PROPAN-2-OL) Fluconazole IMpurity I 4-amino-1-[(2RS)-2-(2,4-difluorophenyl)-2-hydroxy-3(1H- 1,2,4-triazol-1-yl)propyl]-4H-1,2,4-triazolium 1,3-Bis(1H-1,2,4-triazol-1-yl)-2-propanone Fluconazole 2,4-Difluorophenyl) 1-(1H, 1-yl-1,2,4 Triazole-2,3-Epoxy propane methane sulfona METHYL 4-BUTYLBENZOATE FLUCONAZOLE IMPURITY C 3,4-Dihydro-1,4-benzoxazine-3-one 6-oxoacetic Acid 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone 2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)-1,2-propanediol alpha-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol Fludarabine phosphate Fluconazole 2-(2-fluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol alpha-(2,4-Difluorophenyl)-alpha-(4H-1,2,4-triazol-4-ylmethyl)-1H-1,2,4-triazole-1-ethanol 4-Amino Fluconazole Bromide

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