ChemicalBook Product Catalog Organic Chemistry Heterocyclic Compounds 2-Methyl-4-isothiazolin-3-one hydrochloride

2-Methyl-4-isothiazolin-3-one hydrochloride

2-Methyl-4-isothiazolin-3-one hydrochloride Basic information
Product Name:2-Methyl-4-isothiazolin-3-one hydrochloride
Synonyms:3(2H)-Isothiazolone,2-methyl-,hydrochloride;MIT HYDROCHLORIDE;2-Methylisothiazol-3-one hydrochloride;2-METHYL-4-ISOTHIAZOLIN-3-ONE HYDROCHLORIDE;2-methyl-2H-isothiazol-3-one hydrochloride;2-METHYL-4-ISOTHIAZOLIN-3-ONE HCL;N-MethylisothiazoloneHCl;ISO-THIAZOLINONE(KATHON)
CAS:26172-54-3
MF:C4H6ClNOS
MW:151.61
EINECS:247-499-3
Product Categories:Amines;Heterocycles;Sulfur & Selenium Compounds
Mol File:26172-54-3.mol
2-Methyl-4-isothiazolin-3-one hydrochloride Structure
2-Methyl-4-isothiazolin-3-one hydrochloride Chemical Properties
density 1.551 at 21℃
vapor pressure 0.777-1Pa at 20-25℃
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
BRN 3993054
Stability:Hygroscopic
LogP-0.44 at 20℃ and pH2
Surface tension71.3mN/m at 1g/L and 20℃
CAS DataBase Reference26172-54-3(CAS DataBase Reference)
EPA Substance Registry System3(2H)-Isothiazolone, 2-methyl-, hydrochloride (26172-54-3)
Safety Information
Hazard Codes C
Risk Statements 34-42/43
Safety Statements 26-36/37/39-45
RIDADR UN 1759 8/PG 2
WGK Germany 3
HS Code 2934100090
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Methyl-4-isothiazolin-3-one hydrochloride Usage And Synthesis
ApplicationMethylisothiazolinone (MIT) has been used:
as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
Uses2-Methyl-4-isothiazolin-3-one Hydrochloride is an isothiazolinone based biocide and preservative used in personal care products. It is also implicated as an allergen. It is also used for controlling microbial growth in water-containing solution.
General Description2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.
Biochem/physiol Actions2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.
storage store at 2°C - 8°C,close container well.
2-Methyl-4-isothiazolin-3-one hydrochloride Preparation Products And Raw materials
Raw materials3-[(3-AMINO-3-OXOPROPYL)DITHIO]PROPANAMIDE-->Sulfuryl chloride
2-TERT-BUTYL-5-CHLORO-ISOTHIAZOL-3-ONE Methylparaben Methyl 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Topotecan hydrochloride AKOS 212-01 Isothiazolinones 4,5-Dichloro-2-octyl-isothiazolone Basic Violet 1 Kresoxim-methyl 5-Chloro-2-(n-octyl-d17)-4-isothiazolin-3-one Methanol 5-Chloro-2-n-octyl-4-isothiazolin-3-one PYRROLIDONE HYDROTRIBROMIDE Methyl acrylate 2-tert-Butyl-5-chloroisothiazol-3(2H)-one 2-Methyl-4-isothiazolin-3-one hydrochloride 5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride
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