TRIMETHYLACETONITRILE

TRIMETHYLACETONITRILE Basic information
Product Name:TRIMETHYLACETONITRILE
Synonyms:2,2-DIMETHYL-PROPANENITRILE;2,2-DIMETHYLPROPIONITRILE;PIVALONITRILE;TERT-BUTYL CYANIDE;TRIMETHYLACETONITRILE;(CH3)3C-CN;2,2-dimethyl-propanenitril;2,2-Dimethylpropionsαurenitril
CAS:630-18-2
MF:C5H9N
MW:83.13
EINECS:211-133-0
Product Categories:Small molecule;Building Blocks;C1 to C5;Chemical Synthesis;Cyanides/Nitriles;Nitrogen Compounds;Organic Building Blocks
Mol File:630-18-2.mol
TRIMETHYLACETONITRILE Structure
TRIMETHYLACETONITRILE Chemical Properties
Melting point 15-16 °C (lit.)
Boiling point 105-106 °C (lit.)
density 0.752 g/mL at 25 °C (lit.)
refractive index n20/D 1.377(lit.)
Fp 40 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
color Clear colorless
Water Solubility Miscible with ethanol, acetone and toluene. Slightly miscible with water.
BRN 1361449
Exposure limitsNIOSH: IDLH 25 mg/m3
CAS DataBase Reference630-18-2(CAS DataBase Reference)
EPA Substance Registry SystemPropanenitrile, 2,2-dimethyl- (630-18-2)
Safety Information
Hazard Codes F,T,Xi
Risk Statements 11-23/24/25-36
Safety Statements 16-36/37/39-45-26-7/9
RIDADR UN 1993 3/PG 2
WGK Germany 3
19
Hazard Note Irritant
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29269090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
TRIMETHYLACETONITRILE Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS LIQUID
UsesTrimethylacetonitrile used as a solvent and as a labile ligand in coordination chemistry. It is also used as an intermediate in organic synthesis. It is used in the presence of titanium(II) chloride and zinc to undergoes reductive coupling reaction of aromatic and aliphatic ketones including acyclic aliphatic ketones to give the corresponding pinacols.
Purification MethodsPurify it by a two-stage vacuum distillation and de-gas by the freeze-pump-thaw technique. Store it under vacuum at 0o. TOXIC, use an efficient fume hood. [Beilstein 2 IV 875.]
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