ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID

4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID

4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID Basic information
Product Name:4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID
Synonyms:4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID;Rivaroxaban Impurity P;Rivaroxaban Related Impurity 1;Rivaroxaban Impurity 18;2-Thiophenecarboxylic acid, 4,5-dichloro-;5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID;4,5-Dichloro-2-thiophenecarboxylic acid
CAS:31166-29-7
MF:C5H2Cl2O2S
MW:197.04
EINECS:1312995-182-4
Product Categories:
Mol File:31166-29-7.mol
4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID Structure
4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID Chemical Properties
Melting point 196-197 °C
Boiling point 315.3±37.0 °C(Predicted)
density 1.708±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO, Methanol (Slightly)
pka3.31±0.10(Predicted)
form Solid
color Pale Beige to Dark Brown
Safety Information
Risk Statements 36/37/38-20/22
Safety Statements 20-26-35
HS Code 29349990
MSDS Information
4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID Usage And Synthesis
Uses4,5-Dichlorothiophene-2-carboxylic Acid is used in the preparation of compounds that have therapeutic BACE1 and BACE2 inhibitors which are used for the treatment of Alzheimer’s disease, type 2 diabetes and other metabolic disorders.
4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Preparation ProductsMethyl 4,5-dichlorothiophene-2-carboxylate
(R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N- ((2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 2-Thiophenecarboxylic acid (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione 5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]- 3-Morpholinone, 4-(2,4-diaMinophenyl)- (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 4-(4-NITROPHENYL)MORPHOLIN-3-ONE 4-(3-AMino-phenyl)-Morpholin-3-one (R)-N-Glycidylphthalimide 3,4,5-TRICHLOROTHIOPHENE-2-CARBOXYLIC ACID AKOS 2108 AKOS 93395 AKOS 206-10 AKOS 91249 4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID AKOS 92473
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