Treprostinil intermediate

Treprostinil intermediate Basic information
Product Name:Treprostinil intermediate
Synonyms:Treprostinil intermediate;(alphaS,1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-5-methoxy-alpha-pentyl-1H-benz[f]indene-1-propanol;(1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol;(1R,2R,3aS,9aS)-1-((S)-3-hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol;(1R,2R,3aS,9aS)-1-((S,E)-3-hydroxyoct-1-en-1-yl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol;Descarboxy Treprostinil;Treprostinil Impurity 2;Treprostinil Impurity 1
CAS:101692-01-7
MF:C22H34O3
MW:346.5
EINECS:
Product Categories:
Mol File:101692-01-7.mol
Treprostinil intermediate Structure
Treprostinil intermediate Chemical Properties
Melting point 71-72 °C
Boiling point 509.0±50.0 °C(Predicted)
density 1.062±0.06 g/cm3(Predicted)
pka15.10±0.40(Predicted)
Safety Information
MSDS Information
Treprostinil intermediate Usage And Synthesis
UsesDescarboxy Treprostinil is an impurity in the synthesis of Treprostinil (T719500), Synthetic analog of Prostacyclin (P839060). Antihypertensive. Treprostinil, marketed under the trade name Remodulin is a medication used to treat pulmonary arterial hypertension (PAH).
Treprostinil intermediate Preparation Products And Raw materials
Treprostinil Ethyl Ester (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]indene-2,5-diol (-)-Treprostinil 15-epi-Treprostinil Treprostinil Methyl Ester REMODULIN 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid,2-(2-hydroxyethylamino)ethanol

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