2,4,6-TRIFLUOROBENZYL AMINE

2,4,6-TRIFLUOROBENZYL AMINE Basic information
Product Name:2,4,6-TRIFLUOROBENZYL AMINE
Synonyms:RARECHEM AL BW 0429;2,4,6-TRIFLUOROBENZYL AMINE;Benzenemethanamine, 2,4,6-trifluoro- (9CI);1-(2,4,6-Trifluorophenyl)methylamine;2,4,6-trifluorobenzylaminine;(2,4,6-Trifluorophenyl)methylamine;Benzenemethanamine, 2,4,6-trifluoro-;Chlorfenvinphos Impurity 7
CAS:214759-21-4
MF:C7H6F3N
MW:161.12
EINECS:
Product Categories:Fluorine series;HALIDE;214759-21-4
Mol File:214759-21-4.mol
2,4,6-TRIFLUOROBENZYL AMINE Structure
2,4,6-TRIFLUOROBENZYL AMINE Chemical Properties
Boiling point 165℃
density 1.320
Fp 63℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
pka8.16±0.10(Predicted)
form liquid
color Colourless
Water Solubility Slightly Soluble in water (1.2 g/L) (25°C).
Sensitive Air Sensitive
Stability:Air Sensitive
Safety Information
Hazard Codes Xi,C
Risk Statements 34
Safety Statements 20-26-36/37/39-45
RIDADR UN2735
Hazard Note Irritant
HazardClass 8
PackingGroup III
HS Code 2921490090
MSDS Information
2,4,6-TRIFLUOROBENZYL AMINE Usage And Synthesis
UsesUsed to prepare dyes. Industrially used in natural gas and refinery process streams. They also are used in polymer industry as monomers. Amines find use as additives for lubricating oils, engine fuels, and asphalt, and are producers of ethanolamines.
Uses2,4,6-Trifluorobenzylamine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
SynthesisPut into 50 gram 2 into 1000ml autoclave, 4,6- trifluorobenzonitriles, 2.5 grams of raney-ni, 75 gram 25% of ammonia, 500 grams of methanol, control temperature to be 90 DEG C, and mixing speed is 350r/min, are passed through hydrogen hydrogenation, hydrogenation pressure 1mpa, logical hydrogen time 8 Hour reaction terminates, filtering catalyst raney-ni, the methanol in distillation gained filtrate, and distillation terminates addition dichloromethane extraction Take, extract elder generation normal pressure concentrated solvent, then vacuum distillation product, obtain 43.6 grams of product, 2,4,6- trifluoromethyl benzonitrile amine contents 99%, yield is calculated as 85% with 2,4,6- trifluorobenzonitriles.
2,4,6-TRIFLUOROBENZYL AMINE Preparation Products And Raw materials
Raw materials2,4,6-Trifluorobenzonitrile-->3,5-Dichloro-2,4,6-trifluorobenzonitrile-->Pentachlorobenzonitrile-->2,4,6-Trifluorobenzaldehyde
5-(PENTAFLUOROBENZOYLAMINO)FLUORESCEIN DIACETATE 3-AMINO-3-PENTAFLUOROPHENYL-PROPIONIC ACID ETHYL ESTER 5-(PENTAFLUOROBENZOYLAMINO)FLUORESCEIN DI-BETA-D-GLUCURONIDE TETRAFLUOROISOPHTHALAMIDE RARECHEM AK HW 0067 N-PENTAFLUOROBENZOYLIMIDAZOLE BUTTPARK 12\02-12 2,4,6-TRIFLUOROBENZAMIDE 3-HYDROXY-2-PENTAFLUOROPHENYL-2,3-DIHYDRO-1H-QUINAZOLIN-4-ONE 3,5-DIMETHYL-1-PENTAFLUOROPHENYLMETHYL-1H-PYRAZOL-4-YLAMINE 5-(PENTAFLUOROBENZOYLAMINO)DIHYDROFLUORESCEIN DIACETATE 3-AMINO-3-PENTAFLUOROPHENYL-PROPIONIC ACID RARECHEM AL BW 0010 5-(PENTAFLUOROBENZOYLAMINO)FLUORESCEIN 5-(PENTAFLUOROBENZOYLAMINO)FLUORESCEIN DI-BETA-D-GLUCOPYRANOSIDE 5-(PENTAFLUOROBENZOYLAMINO)FLUORESCEIN DI-BETA-D-GALACTOPYRANOSIDE 2,4,6-TRIFLUOROBENZYL AMINE AKOS B014380

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