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Cefpirome sulfate

Cefpirome sulfate Basic information
Product Name:Cefpirome sulfate
Synonyms:1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5h-cyclopenta[b]pyridinium sulfate;CEFPIROME SULFATE;Keitin);Cefquinome base;CefpiromeSulfate3%;1-(((6R,7R)-7-((Z)-2-(2-AMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)Methyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-1-iuM hydrogensulfate;CEFPIROME SULFATE USP 27;(6r-rboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-
CAS:98753-19-6
MF:C22H24N6O9S3
MW:612.66
EINECS:685-392-7
Product Categories:api;Pharmaceutical intermediate;cephalosporins antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical raw material;Antibacterial;Miscellaneous;98753-19-6
Mol File:98753-19-6.mol
Cefpirome sulfate Structure
Cefpirome sulfate Chemical Properties
Melting point 198-2020C (dec)
alpha 25D -4.7° (c = 5 in H2O)
RTECS UW8970000
storage temp. Inert atmosphere,2-8°C
solubility Soluble in DMSO
form Solid
color White to Off-White
λmax265nm(Buffer)(lit.)
Merck 14,1940
CAS DataBase Reference98753-19-6(CAS DataBase Reference)
Safety Information
HS Code 2941.90.3000
MSDS Information
Cefpirome sulfate Usage And Synthesis
DescriptionCefpirome sulfate is a new injectable cephalosporin indicated for the treatment of severe urinary and respiratory tract infections, including septicemia and nosocomial infections. Cefpirome sulfate is reported to be the first true fourth-generation cephalosporin due to its similar activities to third-generation antibiotics against Gram-positive bacteria and to first-generation antibiotics against Gram-negative bacteria. Its efficacy against P.aeruginosa is comparable to ceftazidime. The broad spectrum of activity includes Klebsiella, methicillin-sensitive staphylococci, penicillin-resistant pneumococci, E.coli which generates extended-spectrum beta-lactamases and multi-resistant organisms such as Citrobacter, Enterobacter and Serratia.
Chemical PropertiesWhite Crystalline Powder
OriginatorHoechst AG (Germany)
UsesA fourth generation cephalosporin antibiotic
DefinitionChEBI: Cefpirome sulfate is an azaheterocycle sulfate salt. It is functionally related to a cefpirome.
Brand nameCefrom (Hoechst-Roussel).
Betaine Acetaminophen Acetylacetone Cefpirome Cefquinome sulfate sulfate Sodium sulfate N-Acetylsulfanilyl chloride Glycine Copper(II) sulfate Sodium thiosulfate pentahydrate Ferrous sulfate monohydrate calcium sulfate Colistin sulfate AMINO ACIDS Ferrous sulfate heptahydrate Cefpirome sulfate Potassium sulfate
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