7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III

7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Basic information
Product Name:7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III
Synonyms:7,10-Bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III;7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III;7,10-Di(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III;7,10-Di-O-[(2,2,2-trichloroethoxy)carbonyl]baccatin III;7,10-DiTroc-10-deacetylbaccatin III;Carbonic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,6-diyl bis(2,2,2-trichloroethyl) Ester;7,10-Troc-10-DAB;0-Troc-10-DAB
CAS:95603-44-4
MF:C35H38Cl6O14
MW:895.39
EINECS:
Product Categories:Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals
Mol File:95603-44-4.mol
7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Structure
7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Chemical Properties
Melting point 232-234℃
Boiling point 896.3±65.0 °C(Predicted)
density 1.56
solubility soluble in Chloroform, Ethyl Acetate
pka12.52±0.70(Predicted)
form Solid
color White
Safety Information
MSDS Information
7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
UsesAn intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.
7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III Preparation Products And Raw materials
Docetaxel (4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid Cabazitaxel N-1 Paclitaxel 10-Deacetylbaccatin III Docetaxel intermediate Cabazitaxel (4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid 7,10-Dimethoxy-10-DAB III 7-O-(TRIETHYLSILYL) BACCATIN III Deacetyltaxol 2',3'-O,N-[(S)-(p-Methoxybenzylidene)]-7-O-(triethylsilyl)paclitaxel 7-{[(2,2,2,-TRICHLOROETHYL)OXY]CARBONYL} BACCATIN III Cabazitaxel N-3 7-Troc-paclitaxel "7-(triMethylsilyl)-13-O-[((4S,5R)-2,4-diphenyl-4,5-dihydro oxazol-5-yl)carbonyl]baccatin Ⅲ (4S,5R)-3-tert-butoxycarbony-2-(4-anisy)-4-phenyl-5-oxazolidinecarboxylic acid

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