4-Bromofluorobenzene

4-Bromofluorobenzene Chemical Properties
Melting point −16 °C(lit.)
Boiling point 150 °C(lit.)
density 1.593 g/mL at 25 °C(lit.)
vapor pressure 4.99hPa at 25℃
refractive index n20/D 1.527(lit.)
Fp 140 °F
storage temp. 2-8°C
solubility 0.136g/l
form Liquid
color Clear colorless
Water Solubility Soluble in water(0.14g/L).
BRN 774102
LogP3.018 at 25℃
CAS DataBase Reference460-00-4(CAS DataBase Reference)
NIST Chemistry Referencep-Bromofluorobenzene(460-00-4)
EPA Substance Registry Systemp-Bromofluorobenzene (460-00-4)
Safety Information
Hazard Codes Xi,F,Xn,T
Risk Statements 10-36/37/38-20-39/23/24/25-23/24/25-11-20/21/22
Safety Statements 26-36-37/39-16-45-36/37-7
RIDADR UN 1993 3/PG 3
WGK Germany 1
RTECS CY9033750
Hazard Note Flammable/Irritant
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29036990
MSDS Information
ProviderLanguage
1-Bromo-4-fluorobenzene English
ACROS English
SigmaAldrich English
ALFA English
4-Bromofluorobenzene Usage And Synthesis
Chemical Propertiesclear colorless liquid
Uses4-Bromofluorobenzene is a dihalogenated benzene used in the preparation of pharmaceutical compounds such as atypical antipsychotic agents.
Uses1-Bromo-4-fluorobenzene is used as an intermediate in the synthesis of atypical antipsychotic agents.
Uses4-Bromofluorobenzene can act like a surrogate standard for the:
determination of toxicity of diesel and water accommodated diesel fraction (WAF), towards microalgal species like Pseudokirchneriella subcapitata and Chlorella sp.MM3, using gas chromatography coupled with mass spectrometry (GC-MS).
determination of the chemicals like benzene, toluene, ethylbenzene and xylene (BTEX) and their stable carbon isotopic values, in gasoline contaminated ground-water, using gas chromatography coupled with mass spectrometry (GC-MS).
DefinitionChEBI: 1-bromo-4-fluorobenzene is a member of the class of bromobenzenes that is bromobenzene carrying a fluoro atom at position 4. It is a member of bromobenzenes and a member of monofluorobenzenes.
General DescriptionColorless liquid.
Air & Water ReactionsHighly flammable. Insoluble in water.
Reactivity ProfileSimple aromatic halogenated organic compounds, such as 4-Bromofluorobenzene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Health HazardACUTE/CHRONIC HAZARDS: Irritant.
Flammability and ExplosibilityFlammable
2-Bromo-5-fluorophenol FENFLURAMINE 2-Bromo-5-fluorotoluene 2,3,4-Trifluorobromobenzene Transfluthrin 1-Bromo-2,4-difluorobenzene 3-Fluorobenzyl bromide 2-BROMO-4,5,6-TRIFLUOROANILINE 2,4-Dibromo-1-fluorobenzene trifluorobenzene 1,2-Dibromotetrafluorobenzene 2-AMINO-3,5-DIBROMO-6-FLUOROBENZOIC ACID Florfenicol 4-Bromofluorobenzene 5-Bromo-2-fluorotoluene 1-Bromo-2,4,5-trifluorobenzene 1,2-Dibromo-4,5-difluorobenzene 1-bromo-2,3,4,6-tetrafluorobenzene

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