ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Bromopyridine 4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER

4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER

4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Basic information
Product Name:4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Synonyms:METHYL 4-BROMOPICOLINATE;METHYL 4-BROMOPYRIDINE-2-CARBOXYLATE;METHYL 4-BROMO-2-PYRIDINECARBOXYLATE;4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 4-bromopyridine-2-carboxylate 97%;4-Bromo-2-pyridinecarboxylic acid methyl ester;Methyl 4-broMopyridine-2-...;Methyl 4-broMopyridine-2-carboxylate, 97+%
CAS:29681-42-3
MF:C7H6BrNO2
MW:216.03
EINECS:803-526-6
Product Categories:blocks;Bromides;Carboxes;Pyridines
Mol File:29681-42-3.mol
4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Structure
4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties
Melting point 54-56
Boiling point 286.0±20.0 °C(Predicted)
density 1.579±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
pka-0.25±0.10(Predicted)
form Solid
Water Solubility Slightly soluble in water.
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
Hazard Note Irritant/Keep Cold
HazardClass IRRITANT
HS Code 2933399990
MSDS Information
4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Usage And Synthesis
Chemical Propertiesyellow solid
UsesIt finds its application as a useful synthetic intermediate and in the straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals. It is used in the synthesis of biaryl mannoside FimH inhibitors for use in urinary infection treatment.
4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materialsMethanol-->Thionyl chloride-->Potassium permanganate-->4-Bromo-2-methylpyridine
Preparation Products4-Bromo-2-pyridinemethanol-->4-phenoxypyridine-2-carboxylic acid
4-Bromopyridine hydrochloride 5-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Methyl 6-amino-3-bromopicolinate Diethyl 4-bromopyridine-2,6-dicarboxylate 6-BROMO-PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER 4-Bromopyridine-2-carboxylic acid 2-AMINO-4-BROMO-6-CARBOXYPYRIDINE METHYL ESTER Dimethyl 2-bromo-2,6-pyridinedicarboxylate 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 4-Bromo-pyridine-2-carboxylic acid ethyl ester 4-BROMO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 4-BROMO-6-METHYL-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
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