(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Basic information
Product Name:(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
Synonyms:1,3-DIOXOLANE-4-CARBOXALDEHYDE, 2,2-DIMETHYL-, (R)-;(R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBALDEHYDE;(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE;(R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE;2,3-O-(R)-ISOPROPYLIDENE-L-GLYCERALDEHYDE;D-(R)-GLYCERALDEHYDE ACETONIDE;R-(+)-Solketaldehyde;D-Glyceraldehyde-acetonide
CAS:15186-48-8
MF:C6H10O3
MW:130.14
EINECS:676-289-8
Product Categories:Asymmetric Synthesis;Building Blocks;C1 to C6;Carbonyl Compounds;Chemical Synthesis;Chiral Building Blocks;Organic Building Blocks;Aldehydes;Chiral Building Blocks;Organic Building Blocks;Heterocyclic Building Blocks;pharmacetical;Chiral Reagents;chiral;API intermediates;Heterocycles
Mol File:15186-48-8.mol
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Structure
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Chemical Properties
alpha 53.8 º (c=2, CHCl3)
Boiling point 139 °C (lit.)
density 1.045 g/mL at 25 °C (lit.)
refractive index n20/D 1.454(lit.)
Fp 143 °F
storage temp. -20°C
solubility Difficult to mix.
form Liquid
color Colorless to Pale Yellow
optical activity[α]22/D +53.8°, c = 2 in chloroform
CAS DataBase Reference15186-48-8(CAS DataBase Reference)
NIST Chemistry ReferenceAcetone D-glyceraldehyde(15186-48-8)
Safety Information
WGK Germany 3
HazardClass 6.1
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Usage And Synthesis
Chemical PropertiesColorless Transparent Liquid
UsesReactant involved in organic reactions including:
  • Henry condensation reactions
  • Synthesis of highly functionalized chiral aziridines
  • Olefination of aldehydes
  • C-H oxidations
  • Aldol-type condensations
  • Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents
  • Hosomi-Sakurai reactions
Uses(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde_x000D__x000D_Discontinued, Unstable (cas# 15186-48-8) is a compound useful in organic synthesis.
Uses(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a reactant involved in organic reactions including:• ;Henry condensation reactions1• ;Synthesis of highly functionalized chiral aziridines2• ;Olefination of aldehydes3• ;C-H oxidations4• ;Aldol-type condensations5• ;Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents6• ;Hosomi-Sakurai reactions7
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Preparation Products And Raw materials
Preparation Products(S)-(+)-(2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE-->D-Glyceraldehyde
DIKEGULAC ACID D-ERYTHRURONOLACTONE ACETONIDE Dacthal 5-BROMO-5-DEOXY-2,3-O-ISOPROPYLIDENE-D-RIBONOLACTONE (4R,5R)-4,5-DIETHOXYCARBONYL-2,2-DIMETHYL DIOXOLANE (2R,3R)-2,3-O-(1-PHENYLETHYLIDENE)-L-TARTARIC ACID DIMETHYL ESTER Dikegulac sodium 5-O-(TERT-BUTYLDIMETHYLSILYL)-2,3-O-ISOPROPYLIDENE-D-RIBONIC ACID GAMMA-LACTONE ALPHA-CHLORO-2,3,5,6-DIISOPROPYLIDENE-D-MANNOSE (4R,5R)-2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DICARBOXYLIC ACID DIMETHYL ESTER β,β'-dimethylglutaric acid Methyl (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate Dimethylaminobenzaldehyde 2,3-O-Isopropylidene-D-ribonic gamma-lactone 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE (4R,5R)-4,5-DI(DIMETHYLAMINOCARBONYL)-2,2-DIMETHYLDIOXOLANE, 99+% (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER 2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonicacidmonohydrate

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