|
| | CALCITONIN, HUMAN Basic information |
| Product Name: | CALCITONIN, HUMAN | | Synonyms: | calcitonin M;THYROCALCITONIN HUMAN;H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2;H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 (DISULFIDE BRIDGE: 1-7);CYST-GLY-ASN-LEU-SER-THR-CYST-MET-LEU-GLY-THR-TYR-THR-GLN-AS-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO NH2;CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2;CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 HUMAN;CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-NH2 (DISULFIDE BRIDGE: 1-7) | | CAS: | 21215-62-3 | | MF: | C151H226N40O45S3 | | MW: | 3417.85 | | EINECS: | 244-276-2 | | Product Categories: | Peptide;Calcitonin and CGRP receptor | | Mol File: | 21215-62-3.mol |  |
| | CALCITONIN, HUMAN Chemical Properties |
| Boiling point | 3061.8±65.0 °C(Predicted) | | density | 1.326±0.06 g/cm3(Predicted) | | RTECS | XP3560000 | | storage temp. | −20°C | | solubility | Soluble in DMSO | | form | powder | | Water Solubility | Soluble to 2 mg/ml in water | | Merck | 13,1642 |
| | CALCITONIN, HUMAN Usage And Synthesis |
| Uses | Regulator (calcium). | | Uses | Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. A carrier peptide that can be used to internalize fusion proteins | | Uses | Calcitonin human has been used to study its ability to stimulate cAMP production post transfection in mammalian cell by activating human CALCRL (calcitonin receptor like receptor gene)- receptor activity-modifying protein 1 (RAMP1) and CTR (calcitonin receptor). | | Brand name | Calcimar (Rhone-
Poulenc Rorer);. | | Biochem/physiol Actions | Calcitonin, also referred to as thyrocalcitonin, is a 32 amino acid peptide hormone, which is present abundantly in seminal plasma compared to serum. It acts as a first messenger and hence regulates the the production of cAMP as well as mammalian sperm function. It also facilitates the regulation of different isoforms of adenylyl cyclase. | | storage | Store at -20°C |
| | CALCITONIN, HUMAN Preparation Products And Raw materials |
|
