ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Hydroxypyridine 2-Hydroxy-3-trifluoromethylpyridine

2-Hydroxy-3-trifluoromethylpyridine

2-Hydroxy-3-trifluoromethylpyridine Basic information
Product Name:2-Hydroxy-3-trifluoromethylpyridine
Synonyms:2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE;3-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDIN-2-ONE;3-(TRIFLUOROMETHYL)-2-PYRIDONE;BUTTPARK 24\01-66;3-(Trifluoromethyl)pyridin-2-one;3-Trifluoromethyl-pyridin-2-ol;2-Hydroxy-3-(trifluoromethyl)pyridine 97%;2-Hydroxy-3-(trifluoromethyl)pyridine97%
CAS:22245-83-6
MF:C6H4F3NO
MW:163.1
EINECS:671-273-7
Product Categories:Fluorine series;blocks;FluoroCompounds;Pyridines;Pyridine
Mol File:22245-83-6.mol
2-Hydroxy-3-trifluoromethylpyridine Structure
2-Hydroxy-3-trifluoromethylpyridine Chemical Properties
Melting point 150-153°C
Boiling point 223.7±40.0 °C(Predicted)
density 1.398±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
pka9.67±0.10(Predicted)
color White to Almost white
LogP0.71 at 25℃
CAS DataBase Reference22245-83-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn,T
Risk Statements 36/37/38-65-20/21/22-20/21-36-25
Safety Statements 26-36/37/39-36-45
RIDADR UN2811
HazardClass IRRITANT
HS Code 29333990
MSDS Information
2-Hydroxy-3-trifluoromethylpyridine Usage And Synthesis
Chemical PropertiesWhite powder
Uses2-Hydroxy-3-trifluoromethylpyridine is a reactant in the synthesis of Pyrido[2,3-b]pyrazine, a TRPV1 antagonist .
2-Hydroxy-3-trifluoromethylpyridine Preparation Products And Raw materials
Preparation Products5-isothiocyanato-3-(trifluoromethyl)picolinonitrile-->5-IODO-3-(TRIFLUOROMETHYL)-2(1H)-PYRIDINONE-->2-CHLORO-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE
3-Trifluoromethylpyridine BUTTPARK 148\07-71 6-METHOXY-5-(TRIFLUOROMETHYL)-3-PYRIDINECARBONITRILE 4-(Trifluoromethyl)pyridine 2-Chloro-3-hydroxypyridine 3-(Trifluoromethyl)benzaldehyde 2-(Trifluoromethyl)benzoic acid 4-Methylpyridine 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE 2-Chloro-3-(trifluoromethyl)pyridine Azamethiphos BUTTPARK 148\07-80 2,4,6-Collidine 3-Hydroxypyridine 2-Hydroxypyridine 2-(Trifluoromethyl)pyridine 2-Hydroxy-3-trifluoromethylpyridine CHLOROPHOSPHONAZO III
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