6-Iodoquinazolin-4-one

6-Iodoquinazolin-4-one Basic information
Product Name:6-Iodoquinazolin-4-one
Synonyms:6-Iodo-4(1H)-quinazolinone;6-Iodo-4-quinazolinol;6-Iodoquin;6-Iodo-4-quinazolinol 6-Iodo-4-quinazolinone;6-iodoquinazolin-4(3H)-one;4-Hydroxy-6-iodoquinazoline;TIMTEC-BB SBB005376;6-Iodoquinazolin-4-one,95+
CAS:16064-08-7
MF:C8H5IN2O
MW:272.04
EINECS:605-218-5
Product Categories:pharmacetical;Lapatinib
Mol File:16064-08-7.mol
6-Iodoquinazolin-4-one Structure
6-Iodoquinazolin-4-one Chemical Properties
Melting point 271°C(lit.)
Boiling point 401.0±47.0 °C(Predicted)
density 2.11±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka1.00±0.20(Predicted)
color White to Off-White
CAS DataBase Reference16064-08-7(CAS DataBase Reference)
Safety Information
Risk Statements 36
Safety Statements 26
HS Code 2914390090
MSDS Information
6-Iodoquinazolin-4-one Usage And Synthesis
Chemical PropertiesWhite Solid
Uses6-Iodoquinazolin-4-one is an intermediate in the synthesis of Lapatinib (L175800).
6-Iodoquinazolin-4-one Preparation Products And Raw materials
Raw materialsAcetic acid-->Potassium hydroxide-->Sodium bisulfite-->Iodine-->Formamide-->Anthranilic acid
Preparation Products5-(4-Hydroxy-6-quinazolinyl)furan-2-carbaldehyde
6-Bromoquinazolin-4-ol 3-(2-(Ethylamino)ethyl)-6-iodo-2-methyl-4(3H)-quinazolinone Naphazoline hydrochloride ZERENEX E/6026490 Cefazolin 6-IODO-2,4-DIMETHOXYQUINAZOLINE 6-IODO-2-METHYL-1H-QUINAZOLIN-4-ONE 2-IODO-7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE 6-iodoquinazoline SALOR-INT L135879-1EA 6,8-DIIODO-4-QUINAZOLONE 2-Ethyl-6-iodo-3-(2-((1-methylethyl)amino)ethyl)-4(3H)-quinazolinone Cefazolin sodium salt 2-AMINO-6-IODO-8-METHYL-1H-QUINAZOLIN-4-ONE N-(6-IODO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINAZOLIN-2-YL)-ISOBUTYRAMIDE 6-Iodoquinazolin-4-one

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