TRIPALMITIN

TRIPALMITIN Basic information
Product Name:TRIPALMITIN
Synonyms:PALMITIN;TRIPALMITIN(RG);Glyceryl tripalmitate,Glycerol tripalmitate, Tripalmitin;Tripalmitin 100mg [555-44-2];TRIHEXADECANOIN;TRIPALMITIN;1,2,3-propanetriyltri(hexadecanoate);1,2,3-tris-hexadecanoyloxy-propane
CAS:555-44-2
MF:C51H98O6
MW:807.32
EINECS:209-098-1
Product Categories:Fatty Acid Derivatives & Lipids;Glycerols
Mol File:555-44-2.mol
TRIPALMITIN Structure
TRIPALMITIN Chemical Properties
Melting point 66-68 °C
Boiling point bp 310-320°
density 0.8752 g/cm3 (70 ºC)
refractive index nD80 1.43807
storage temp. -20°C
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Hexanes (Very Slightly)
form Fine Crystalline Powder
color White to almost white
Merck 14,9736
BRN 1811188
LogP21.615 (est)
CAS DataBase Reference555-44-2(CAS DataBase Reference)
EPA Substance Registry SystemTripalmitin (555-44-2)
Safety Information
Hazard Codes Xn
Risk Statements 20/22
Safety Statements 22-24/25
WGK Germany -
RTECS RT4953500
TSCA Yes
HS Code 29157090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
TRIPALMITIN Usage And Synthesis
Description1,2,3-Tripalmitoyl glycerol is a triacylglycerol that contains palmitic acid at the sn-1, sn-2, and sn-3 positions and has been found in palm oil. It inhibits glucose-stimulated insulin secretion and reduces viability of INS1 cells in a concentration-dependent manner. Myocardial levels of 1,2,3-tripalmitoyl glycerol are elevated by greater than 5-fold in a rat model of diabetes induced by streptozotocin . 1,2,3-Tripalmitoyl glycerol has been used to form the lipid matrices of etoposide-incorporated nanoparticles. Formulations containing 1,2,3-tripalmitoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents.
Chemical PropertiesWhite, crystalline powder. Soluble in ether and chloroform; insoluble in water. Combustible.
UsesTripalmitin is a triglyceride derived from Palmitic Acid (P144500), a common fatty acid found in plants and animals. Tripalmitin is used in the preparation of solid lipid particles for oral delivery of drugs.
UsesSoap, leather dressing.
UsesGlyceryl tripalmitate has been used as a reference standard
  • for the generation of calibration curve generation for the quantification of lipids from Azospirillum brasilense
  • for the quantification of silk worm embryos and extraembryonic yolk lipids using thin layer chromatography
  • for the quantification of triacylglycerol in Neochloris minuta microalgal cells

DefinitionChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by palmitic (hexadecanoic) acid.
General DescriptionSRM 1595_cert SRM 1595 _SDS
Biochem/physiol ActionsGlyceryl tripalmitate is a carrier molecule for effective drug delivery and is used solid lipid nanoparticle formulations.
Purification MethodsCrystallise it from acetone, diethyl ether or EtOH. It exists in an -form (m 56.0o), a ’-form (m 63.5o) and a -form (m 65.5o). [Beilstein 2 H 373, 2 I 167, 2 II 340, 2 III 971.]
TRIPALMITIN Preparation Products And Raw materials
Preparation Products1-Hexadecylamine-->N,N'-ethane-1,2-diylbishexadecan-1-amide-->PALMITIC ACID PROPYL ESTER-->Cholesteryl palmitate
1,3-STEARIN-2-PALMITIN Glycerol tristearate TRILIGNOCERIN TRITRICOSANOIN GLYCERYL TRI[9-EPOXY-12-ACETOXYSTEARATE] TRIARACHIDIN TRIPALMITIN, [PALMITIC-1-14C] 1,2,3-TRINONADECANOYLGLYCEROL 1,2-DIOCTADECANOYL-3-HEXADECANOYL-RAC-GLYCEROL TRIPALMITIN (2,2,2-13C3) TRIHENEICOSANOIN TRIPALMITIN (2-PALMITOYL-2-13C) TRIBEHENIN GLYCERYL TRIACETYLSTEARATE 1,3-PALMITIN-2-STEARIN 1,1,1-13C-TRIPALMITIN TRIPALMITIN 1,2-PALMITIN-3-STEARIN

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