1-METHYLURACIL

1-METHYLURACIL Basic information
Product Name:1-METHYLURACIL
Synonyms:2,4(1H,3H)-Pyrimidinedione, 1-methyl-;1-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione;NSC 44432;1-METHYLURACIL;1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE;1-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE;1-METHYL-1H-PYRIMIDINE-2,4-DIONE;METHYLURACIL
CAS:615-77-0
MF:C5H6N2O2
MW:126.11
EINECS:
Product Categories:Heterocyclic Compounds;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Heterocycles
Mol File:615-77-0.mol
1-METHYLURACIL Structure
1-METHYLURACIL Chemical Properties
Melting point 236-238 °C (lit.)
Boiling point 234.21°C (rough estimate)
density 1.3541 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility 1 M NaOH: soluble50mg/mL, clear, colorless
pka9.77±0.10(Predicted)
form Solid
color White
Water Solubility 20g/L(temperature not stated)
CAS DataBase Reference615-77-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 40
Safety Statements 22-36
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
1-METHYLURACIL Usage And Synthesis
Chemical PropertiesCrystalline Solid
Uses1-Methyluracil (cas# 615-77-0) is a compound useful in organic synthesis.
DefinitionChEBI: A pyrimidone that is uracil with a methyl group substituent at position 1.
General Description1-Methyluracil is of special importance in biochemistry, since uracil attaches ribose in ribonucleic acid (RNA) just precisely at the N1 atom. H-bond complex formation between 1-methyluracil and glycine has been investigated by theoretical calculations and FT-IR spectroscopy in Ar matrices. It forms 1:1 complexes with 9-ethyl-8-bromo-2,6-diaminopurine and the complex structure has been determined by three-dimensional X-ray diffraction methods.
1-METHYLURACIL Preparation Products And Raw materials
Preparation Products1-METHYLCYTOSIN-->2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-(trifluoromethyl)--->2(1H)-Pyrimidinone, 4-(dimethylamino)-1-methyl-
3-METHYLURACIL 1-(2-Propenyloxymethyl)-5-methyluracil 5-IODO-1,3-DIMETHYLURACIL 6-Methyluracil 5-Methyluridine 6-amino-5-formamido-1,3-dimethyluracil 1,3-Bis(2-propenyloxymethyl)-5-methyluracil 3-Benzyl-5-methyluracil 3-Benzyl-6-methyluracil 1-(2-HYDROXYETHOXY)METHYL-5-METHYLURACIL 3-tert-butyl-6-methyluracil 1-[1-(2-Propenyloxy)propyl]-6-methyluracil 1,3-Dibenzyl-5-methyluracil 1,3-Dimethyluracil 5,6-Diamino-1,3-dimethyluracil hydrate 1-(3-Deoxy-3-fluoro-2-O,5-O-ditrityl-β-D-xylofuranosyl)-3-methyluracil 1-(4-Bromophenyl)-5-(dimethylamino)-3-methyluracil 1-[2-DEOXY-ALPHA-D-RIBOFURANOSYL]-5-METHYLURACIL

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