4-Chlorobenzyl chloride

4-Chlorobenzyl chloride Basic information
Product Name:4-Chlorobenzyl chloride
Synonyms:(4-chlorophenyl)methylchloride;,4-Dichlorotoluene;1-chloro-4-(chloromethyl)-benzen;1-CHLORO-4-(CHLOROMETHYL)-BENZENE;PCBC;P-CHLOROBENZYL CHLORIDE;4,ALPHA-DICHLOROTOLUENE;4-CHLOROBENZYL CHLORIDE
CAS:104-83-6
MF:C7H6Cl2
MW:161.03
EINECS:203-242-7
Product Categories:alkyl chloride;Aryl;Building Blocks;C7;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;Pesticides intermediate
Mol File:104-83-6.mol
4-Chlorobenzyl chloride Structure
4-Chlorobenzyl chloride Chemical Properties
Melting point 27-29 °C (lit.)
Boiling point 216-222 °C (lit.)
density 1.26
refractive index 1.5575
Fp 208 °F
storage temp. Store at RT.
solubility insoluble
form Crystalline Low Melting Solid
color Colorless to white
Specific Gravity1.26
Water Solubility insoluble
Sensitive Lachrymatory
BRN 471558
Stability:Moisture Sensitive
CAS DataBase Reference104-83-6(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1-chloro-4-(chloromethyl)-(104-83-6)
EPA Substance Registry System4-Chlorobenzyl chloride (104-83-6)
Safety Information
Hazard Codes C,N,Xn
Risk Statements 34-51/53-20/21/22-52/53-43-22
Safety Statements 26-36/37/39-45-29-61-36/37
RIDADR UN 3427 6.1/PG 3
WGK Germany 2
RTECS XT0720000
19-21
Hazard Note Corrosive/Lachrymatory
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29049090
Hazardous Substances Data104-83-6(Hazardous Substances Data)
MSDS Information
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4-Chlorobenzyl chloride English
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4-Chlorobenzyl chloride Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
UsesReagent used in derivatization of, for example, a calix[4]arene1 and a tryptamine.2
Uses4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.
Uses4-Chlorobenzyl chloride was the test compound for determining rat hepatocellular thiols by HPLC. As a reagent used in derivatization of, for example, a calix[4]arene and a tryptamine. It is widely used as an intermediate for manufacturing organic compounds like benzyl alcohol and benzyl cyanide. Also used in fuel as a gum inhibitor.
General Description4-Chlorobenzyl chloride is generally used in the preparation of quaternary ammonium salts. It acts as an intermediate in the production of rice herbicide, pharmaceuticals and pesticides.
HazardIrritating to skin, eyes.
Purification MethodsDry it over CaSO4, then fractionally distil it under reduced pressure. Crystallise it from heptane or dry diethyl ether at low temperature. [Beilstein 5 IV 816.] LACHRYMATORY.
BENZAL CHLORIDE 4-Chlorobenzylamine 4-Methylbenzyl chloride Benzyl chloride Benzyltriethylammonium chloride 4-Chlorobenzyl alcohol Calcium chloride Phenylacetone Sodium chloride 2-(4-Chlorobenzyl)pyridine Benzyltrimethylammonium chloride Choline chloride Ammonium chloride Benzyl chloroformate Polyvinyl chloride Thionyl chloride 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile Diethylstilbestrol

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