ChemicalBook Product Catalog Biochemical Engineering Plant extracts Licochalcone B

Licochalcone B

Licochalcone B Basic information
Product Name:Licochalcone B
Synonyms:3,4,4'-Trihydroxy-2-Methoxychalcone;LICOCHALCONEB;(E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one;3,4,4'-Trihydroxy-2-methoxy-trans-chalcone;2-Propen-1-one,3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-;Licoagrochalcone B;(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
CAS:58749-23-8
MF:C16H14O5
MW:286.28
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:58749-23-8.mol
Licochalcone B Structure
Licochalcone B Chemical Properties
Melting point 196-197℃
Boiling point 550.5±50.0 °C(Predicted)
density 1.369±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Store at -20°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
pka7.80±0.15(Predicted)
color White
Safety Information
MSDS Information
Licochalcone B Usage And Synthesis
Chemical PropertiesLicochalcone B is a yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents,and it is derived from licorice rhizomes.
UsesLicochalcone B has anti-tumor, anti-inflammatory, and antioxidant effects.It can be used for content determination, identification, pharmacological experiments, etc.
DefinitionChEBI: Licochalcone B is a member of chalcones.
Biological ActivityLicochalcone B is extracted from Glycyrrhizainflate root. LICOCHALCONEB inhibits the self-aggregation of amyloid β (Aβ420) (IC50=2.16 μM) and disintegrates pre-formed Aβ42 fibrils, reducing metal-induced Aβ42 aggregation by chelating metal ions.
isoliquiritin apioside Glycyrrhizic acid Licochalcone E ISOLIQUIRITIN LICOCHALCONEC Glabrone 3β,22β-Dihydroxy-11-oxoolean-12-en-30-oic acid γ-lactone 2-Propen-1-one, 3-(3,4-dihydroxy-2-Methoxyphenyl)-1-[4-hydroxy-3-(3-Methyl-2-butenyl)p henyl]-, (E)- LICOCHALCONE-A Licoflaven B 5,7-Dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one Dipotassium glycyrrhizinate Neoisoliquiritin GLABROL Isoliquiritigenin Licoflavone C neoliquiritin trans-Chalcone
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