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| | 6 beta-hydroxycortisol Basic information |
| Product Name: | 6 beta-hydroxycortisol | | Synonyms: | (6β,11β)-;Hydrocortisone IMpurity D;(6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-diMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one;(6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione;6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione;6,17-Dihydroxycorticosterone;NSC 76163;Hydrocortisone impurity D (EP) | | CAS: | 53-35-0 | | MF: | C21H30O6 | | MW: | 378.46 | | EINECS: | | | Product Categories: | Metabolites & Impurities;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 53-35-0.mol |  |
| | 6 beta-hydroxycortisol Chemical Properties |
| Melting point | 182-190?C | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Pale Yellow |
| | 6 beta-hydroxycortisol Usage And Synthesis |
| Chemical Properties | Off-White to Pale Yellow Solid | | Uses | A metabolite of Cortisol | | Definition | ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol. |
| | 6 beta-hydroxycortisol Preparation Products And Raw materials |
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