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BERBAMINE DIHYDROCHLORIDE

BERBAMINE DIHYDROCHLORIDE Basic information
Product Name:BERBAMINE DIHYDROCHLORIDE
Synonyms:BERBENINE;BERBAMINE DIHYDROCHLORIDE;BERBAMINE HCL;BERBAMINE 2HCL;(4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-21,22,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-12-ol hydrochloride;6,6',7-Trimethoxy-2,2'-dimethylberbaman-12-ol dihydrochloride;Berbaman-12-ol,6,6',7-trimethoxy-2,2'-dimethyl-, dihydrochloride (9CI);Berbamine dihydrochloride, >95%
CAS:6078-17-7
MF:C37H42Cl2N2O5
MW:665.65
EINECS:200-001-8
Product Categories:reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;chemical reagent;pharmaceutical intermediate;phytochemical;Inhibitors
Mol File:6078-17-7.mol
BERBAMINE DIHYDROCHLORIDE Structure
BERBAMINE DIHYDROCHLORIDE Chemical Properties
Melting point 250-253 °C(lit.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility ≥68 mg/mL in DMSO; ≥10.68 mg/mL in H2O; ≥4.57 mg/mL in EtOH
form solid
optical activity[α]20/D +116°, c = 1% in ethanol
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
BERBAMINE DIHYDROCHLORIDE Usage And Synthesis
UsesReactant for:
  • Preparation of and anti-leukemia active berbamine derivatives
Uses(+)-Berbamine Dihydrochloride exerts anti-inflammatory effects through inhibition of NF-κB and MAPK signalling pathways.
Biological Activityextracted from berberidis;store the product in sealed, cool and dry condition
targetcAMP | Calcium Channel
BERBAMINE DIHYDROCHLORIDE Preparation Products And Raw materials
3-PHENOXYPHENETHYLAMINE 1,2-DIMETHYL-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE 2,4-Dimethoxybenzylamine hydrochloride 2,3,4-Trimethoxybenzylamine 7,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride CHEMBRDG-BB 5209105 6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE, 99 1-BENZYL-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE (R)-1-(3-Methoxyphenyl)ethylamine (R)-1-(2-Methoxyphenyl)ethylamine SALSOLIDINE 1-(2-PHENOXYPHENYL)METHANAMINE HYDROCHLORIDE BERBAMINE 2,2',3-TRIHYDROXYDIPHENYL ETHER N-Methyl-3-phenoxybenzylamine 3,5-DIMETHOXY-4-HYDROXYPHENETHYLAMINE HYDROCHLORIDE 3-Phenoxybenzylamine hydrochloride TIMTEC-BB SBB005977
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