ChemicalBook Product Catalog Analytical Chemistry Analysis reagents Ion chromatography reagents 4-Acetoxyacetanilide

4-Acetoxyacetanilide

4-Acetoxyacetanilide Basic information
Product Name:4-Acetoxyacetanilide
Synonyms:(4-acetamidophenyl) ethanoate;acetic acid (4-acetamidophenyl) ester;4-Acetylaminophenol acetate;Acetic acid 4-(acetylamino)phenyl ester;Acetaminophen Impurity 2;Paracetamol Impurity H;Paracetamol EP Impurity H;Paracetamol Impurity 8(Paracetamol EP Impurity H)
CAS:2623-33-8
MF:C10H11NO3
MW:193.2
EINECS:220-077-6
Product Categories:Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:2623-33-8.mol
4-Acetoxyacetanilide Structure
4-Acetoxyacetanilide Chemical Properties
Melting point 155°C
Boiling point 329.41°C (rough estimate)
density 1.2307 (rough estimate)
refractive index 1.5300 (estimate)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form neat
pka14.41±0.70(Predicted)
color White to Off-White
Water Solubility 0.32g/L(25 ºC)
CAS DataBase Reference2623-33-8(CAS DataBase Reference)
EPA Substance Registry System4-Acetoxyacetanilide (2623-33-8)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
WGK Germany 3
HS Code 2924296000
MSDS Information
4-Acetoxyacetanilide Usage And Synthesis
Chemical PropertiesWhite Solid
Usesanalgesic, antiinflammatory
UsesA synthetic impurity of Acetaminophen
Application4′-Acetoxyacetanilide may be used as a reference standard for the determination of 4′-acetoxyacetanilide in pharmaceutical formulations by high performance liquid chromatography (HPLC) technique.
General Description4′-Acetoxyacetanilide is an impurity of Acetaminophen, or Paracetamol as known internationally. This certified solution standard can be used for multiple HPLC applications including pharmaceutical testing, research, and Monograph testing methods. Acetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers).
4-Acetoxyacetanilide Preparation Products And Raw materials
Preparation Products4-Amino-3-nitrophenol-->3,5-dichloro-1,4-aminophenol-->4-IODO-3-NITROPHENOL-->2-BENZYL-4-METHYL-PYRROLO(3,4-C)QUINOLINE-1,3-DIONE
6-ACETAMIDOCOUMARIN SUC-ALA-ALA-PRO-VAL-AMC 2-Propenoic acid, 2-methyl-, 4-(acetylamino)phenyl ester 4-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)PHENYL ACETATE BENORILATE Propacetamol AKOS AUF0220 Diloxanide furoate MEOSUC-GLY-LEU-PHE-AMC H-VAL-AMC TFA PARACETAMOL IMP. H (EP): 4-(ACETYLAMINO)PHENYL ACETATE(N,O-DIACETYL-4-AMINOPHENOL) 4'-ACETAMIDOPHENYL 4-GUANIDINOBENZOATE HYDROCHLORIDE Pidolacetamol SUC-TYR-VAL-ALA-ASP-AMC PARACETAMOL IMP. H (EP): N,O-DIACETYL-4-AMINOPHENOL MM(CRM STANDARD) 4-Acetoxy-1-acetylamino-2-nitro-benzene 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER 4-(acetylamino)phenyl N-acetyl-DL-methionate
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