|
| | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Basic information |
| Product Name: | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- | | Synonyms: | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)-;(+)-6-Methyl-1,2,10-trimethoxy-5,6,6aα,7-tetrahydro-4H-dibenzo[de,g]quinoline-9-ol;(+)-N-Methyllaurotetamine;(6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-ol;Lauroscholtzine;Methyllaurotetanine;Rogersine;Boldine 2-methyl ether | | CAS: | 2169-44-0 | | MF: | C20H23NO4 | | MW: | 341.4 | | EINECS: | | | Product Categories: | | | Mol File: | 2169-44-0.mol |  |
| | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Chemical Properties |
| Melting point | 102.5°C | | Boiling point | 477.03°C (rough estimate) | | density | 1.2064 (rough estimate) | | refractive index | 1.5614 (estimate) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Usage And Synthesis |
| Description | This alkaloid, identified as the N-methyl derivative of laurotetanine (q. v.), has
been isolated from Escholtzia californica Cham., Phylica fengerialla and P.
rogersii Pillans. The base is known in two modifications; as an amorphous
powder and a colourless crystals from MeOH containing 0.5 mole of solvent,
identical with rogersine (q.v.). The alkaloid has [α]D + 1110 (c 0.86, MeOH) and
the ultraviolet spectrum in EtOH has absorption maxima at 219, 282 and
304 rn[J.; while that in alkaline solution (0.05 N/NaOH) has absorption maxima
at 223 and 329 mil.
The alkaloid yields a crystalline hydriodide, m.p. 245°C; the methiodide,
m.p. 199-2000 C and the Q-ethyl (-)-tartrate, m.p. 206-7°C (dec.) giving a
methiodide, m.p. 213° C. | | target | 5-HT Receptor | Antifection | | References | Arndt, Baarschers., J. Chern. Soc., 2244 (1964)
Manske, Shin., Can. J. Chern., 43,2180 (1965)
Baarschers, Arndt., Tetrahedron, 21,2155 (1965)
Pachler, Arndt, Baarschers., ibid, 21,2159 (1965) |
| | 4H-Dibenzo(de,g)quinolin-9-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6 -methyl-, (S)- Preparation Products And Raw materials |
|
