Columbianadin

Columbianadin Basic information
Product Name:Columbianadin
Synonyms:(S)-8-[1-[(Z)-2-Methyl-2-butenoyloxy]-1-methylethyl]-8,9-dihydro-2H-furo[2,3-h]-1-benzopyran-2-one;Columbianadin;ColuMbianin;ZosiMin;Columbianetin angelate;Columbianadin, 98%, from Angelica pubescens Maxim.f. biserrata Shan et Yuan;Columbianadin 5058-13-9;Columbianadin Columbianadin
CAS:5058-13-9
MF:C19H20O5
MW:328.36
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:5058-13-9.mol
Columbianadin Structure
Columbianadin Chemical Properties
Melting point 117.0 to 121.0 °C
Boiling point 482.3±45.0 °C(Predicted)
density 1.232±0.06 g/cm3(Predicted)
solubility DMSO : 33.33 mg/mL (101.50 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form powder to crystal
color White to Almost white
Safety Information
Safety Statements 24/25
HS Code 29329990
MSDS Information
Columbianadin Usage And Synthesis
UsesColumbianedin, a coumarin compounds, is one of the main bioactive constituents of Angelica pubescens Maxim f. biserrata Shan et Yuan and is studied for its antiinflammatory and analgesic properties. Potential anti-tumor agent. Cytotoxic.
DefinitionChEBI: Columbianadin is an alpha,beta-unsaturated carboxylic ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. It has a role as an anti-inflammatory agent, an apoptosis inducer, a hepatoprotective agent, an antineoplastic agent, a rat metabolite and a plant metabolite. It is a furanocoumarin and an alpha,beta-unsaturated carboxylic ester. It is functionally related to an angelic acid.
Columbianadin Preparation Products And Raw materials
Glycerin Rosin Ester Saikosaponin D Saikosaponin C Kalii Dehydrographolidi Succinas Bonvalotidine A CETEARYL OLIVATE Anemoside A3 Pulchinenoside A3 Dihydropyrazine Neopentyl glycol diheptanoate IRISFLORENTIN Penicillin G sodium salt 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate 2-PHENOXYETHYL METHACRYLATE COLUMBIANETIN ACETATE columbianetin Columbianadin ARCHANGELICIN 3-PHENYLPROPYL METHACRYLATE

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