Phthaloyl amlodipine

Phthaloyl amlodipine Basic information
Product Name:Phthaloyl amlodipine
Synonyms:3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate;1-Amino-6-fluoro-1,4-dihydro-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)piperazin-1-yl)-4-oxo-[1,3]thiazeto[3,2-A]quinoline-3-carboxylic acid;3-Ethyl-5-methyl-4-(2-chlorophenyl)-2-(2-phthalimidoethoxyl)methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-(phthalimidoethoxy)methyl-1,4-dihydropyridine;Phthalimidoamlodipine;3,5-Pyridinedicarboxylicacid,4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-,3-ethyl 5-Methyl ester;4-(2-Chlorophenyl)-3-Ethoxy carbonyl-5-Methoxy carbonil-6-Methyl-2-(phthaliMidoethoxy)Methyl-1,4-dihydropyridine;4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
CAS:88150-62-3
MF:C28H27ClN2O7
MW:538.98
EINECS:413-410-3
Product Categories:Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API intermediates;Aromatics
Mol File:88150-62-3.mol
Phthaloyl amlodipine Structure
Phthaloyl amlodipine Chemical Properties
Melting point 140-145°C
Boiling point 654.1±55.0 °C(Predicted)
density 1.321±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
pka2.06±0.70(Predicted)
form neat
color Pale Yellow to Light Yellow
PH6.78 at 20.4℃ and 10g/L
LogP4.9 at 30℃ and pH6.79
CAS DataBase Reference88150-62-3(CAS DataBase Reference)
Safety Information
Risk Statements 53
Safety Statements 61
HS Code 2933399090
MSDS Information
Phthaloyl amlodipine Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesAmlodipine intermediate. Amlodipine Related Compound A
UsesAmilodopine intermediate
Methyl (S)-Amlodipine Amlodipine Besylate 3,4'-DIAMINODIPHENYLMETHANE Ethoxyquin Ethyl 3-amino-4-(2-phthalimidoethoxy)crotonate acetic acid, triethoxy-, ethyl ester Desmethyl amolodipine (S)-AMlodipine-d4 AMlodipine IMpurity F Maleate diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)Methyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate Amlodipine Impurity 13 3,5-Pyridinedicarboxylicacid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Amlodipine Impurity 25 Amlodipine Impurity 48 d-Amlodipine Amlodipine iMpurity K Amlodipine Impurity 10

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