Diethyl (tosyloxy)methylphosphonate

Diethyl (tosyloxy)methylphosphonate Basic information

Product Name:	Diethyl (tosyloxy)methylphosphonate
Synonyms:	DIETHYL 4-TOLUENESULFONYLOXYMETHYLPHOSPHONATE;diethyl [[[(4-tolyl)sulfonyl]oxy]methyl]phosphonate;(DIETHOXYPHOSPHORYL)METHYL 4-METHYLBENZENESULFONATE;[[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic acid diethyl ester;tosyloxymethyl diethyl phosphonate;TOLUENE-4-SULFONIC ACID DIETHOXY-PHOSPHORYLMETHYL ESTER;DESMP;DETHYL (TOSYLOXY) METHYLPHOSPHONATE
CAS:	31618-90-3
MF:	C12H19O6PS
MW:	322.31
EINECS:	608-653-9
Product Categories:	Intermediates.;Phospholipids - 13C & 2H;Phosphorylating and Phosphitylating Agents
Mol File:	31618-90-3.mol

Diethyl (tosyloxy)methylphosphonate Chemical Properties

Boiling point	137°C/0.02mmHg(lit.)
density	1.255
refractive index	1.4980 to 1.5020
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Sparingly), Dichloromethane, Ethyl Acetate, Methanol (Sparingly)
form	Oil
color	Clear Colourless to Pale Yellow
InChI	InChI=1S/C12H19O6PS/c1-4-16-19(13,17-5-2)10-18-20(14,15)12-8-6-11(3)7-9-12/h6-9H,4-5,10H2,1-3H3
InChIKey	UOEFFQWLRUBDME-UHFFFAOYSA-N
SMILES	P(COS(C1=CC=C(C)C=C1)(=O)=O)(=O)(OCC)OCC
CAS DataBase Reference	31618-90-3(CAS DataBase Reference)

Safety Information

MSDS Information

Diethyl (tosyloxy)methylphosphonate Usage And Synthesis

Chemical Properties	Pale Yellow Oil
Uses	Diethyl (tosyloxy)methylphosphonate is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.
Uses	Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.

Diethyl (tosyloxy)methylphosphonate Preparation Products And Raw materials

Preparation Products

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