8-isopropyl-8-azabicyclo[3.2.1]octan-3-one

8-isopropyl-8-azabicyclo[3.2.1]octan-3-one Basic information
Product Name:8-isopropyl-8-azabicyclo[3.2.1]octan-3-one
Synonyms:8-isopropyl-8-azabicyclo[3.2.1]octan-3-one;8-(1-METHYLETHYL)-8-AZABICYCLO(3.2.1)OCTAN-3-NONE;8-(1-Methylethyl)-8-azabicyclo[3.2.1]octan-3-one;8-Isopropyl-8-azabicyclo[3.2.1]octane-3-one;N-Isopropylnortropinone;Einecs 222-315-4;8-Isopropylnortropinone;Isopropyl nortropinone
CAS:3423-28-7
MF:C10H17NO
MW:167.25
EINECS:222-315-4
Product Categories:
Mol File:3423-28-7.mol
8-isopropyl-8-azabicyclo[3.2.1]octan-3-one Structure
8-isopropyl-8-azabicyclo[3.2.1]octan-3-one Chemical Properties
Boiling point 254.7±15.0 °C(Predicted)
density 1.028±0.06 g/cm3(Predicted)
storage temp. Room Temperature
solubility Ethyl Acetate; Dichloromethane; Chloroform;
form Colorless Liquid
pka9.09±0.20(Predicted)
Safety Information
MSDS Information
8-isopropyl-8-azabicyclo[3.2.1]octan-3-one Usage And Synthesis
Chemical PropertiesWhite needle like crystals
Uses(1R,5S)-8-Isopropyl-8-azabicyclo[3.2.1]octan-3-one is an intermediate for the synthesis of (S)-(1R,3r,5S)-8-Isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-Hydroxy-2-phenylpropanoate (I824270), which is a compound that can be synthesized from Atropine (A794630), a nerve agent that occurs naturally in plants of the nightshade family.
8-isopropyl-8-azabicyclo[3.2.1]octan-3-one Preparation Products And Raw materials
Raw materials2,5-Dimethoxytetrahydrofuran-->Trisodium citrate dihydrate-->Isopropylamine
IpratropiuM BroMide IMpurity E endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol Atropic acid IpratropiuM BroMide IMpurity F (Mixture of DiastereoMers) (endo,anti)-(±)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide N-isopropyltropinium Nortropan-3-one (R)-2-Phenyl-3-hydroxypropionic acid Atropine EP Impurity D and E (Mixture of 6-beta-Hydroxyhyoscyamine and 7-beta-Hydroxyhyoscyamine) APOATROPINE littorine 6-beta-hydroxyl tropine (S)-Tropic acid Atropine EP Impurity G (Racemic Littorine) Noratropine Atropine sulfate Atropine Impurity 5 (Mixture of Isomers) HYOSCYAMINE RELATED COMPOUND A (10 MG) (NORHYOSCYAMINE SULFATE)

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