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| | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Basic information |
| Product Name: | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione | | Synonyms: | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione;16β-Methyl-17,21-dihydroxypregna-1,4,9(11)-triene-3,20-dione;Betamethasone EP Impurity C;(8S,10S,13S,14S,16S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one;(8S,10S,13S,14S,16S,17R);Betamethasone Impurity 3（Betamethasone EP Impurity C）;Betamethasone impurity 2/Betamethasone EP Impurity C/(8S,10S,13S,14S,16S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one;Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-16-methyl-, (16β)- | | CAS: | 13504-15-9 | | MF: | C22H28O4 | | MW: | 356.46 | | EINECS: | 236-830-7 | | Product Categories: | | | Mol File: | 13504-15-9.mol |  |
| | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Chemical Properties |
| Melting point | 209-212 °C(Solv: acetone (67-64-1); hexane (110-54-3)) | | Boiling point | 548.3±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | solubility | Acetone (Slightly), Chloroform (Slightly) | | form | Solid | | pka | 12.53±0.70(Predicted) | | color | White to Off-White |
| | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Usage And Synthesis |
| Uses | (16b)-17,21-Dihydroxy-16b-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient. |
| | 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Preparation Products And Raw materials |
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