ChemicalBook Product Catalog API Nervous system drugs Sedative and hypnotic Doxefazepam

Doxefazepam

Doxefazepam Basic information
Product Name:Doxefazepam
Synonyms:doxefaxepam;Doxefazepam;1,3-Dihydro-7-chloro-5-(o-fluorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-2H-1,4-benzodiazepin-2-one;7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-(2-hydroxyethyl)-2H-1,4-benzodiazepin-2-one;Doxans;SAS-643;Doxefazepam USP/EP/BP;DUFLURAZEPAM
CAS:40762-15-0
MF:C17H14ClFN2O3
MW:348.76
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Mol File:40762-15-0.mol
Doxefazepam Structure
Doxefazepam Chemical Properties
Melting point 138-140°
Boiling point 204.52°C (rough estimate)
density 1.3534 (estimate)
storage temp. Store at -20°C
pka11.55±0.40(Predicted)
IARC3 (Vol. 66) 1996
Safety Information
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
ToxicityLD50 in rats, mice (mg/kg): 2550, >1500 orally; 586, 774 i.p. (Babbini)
MSDS Information
Doxefazepam Usage And Synthesis
DescriptionDoxefazepam is a benzodiazepine hypnotic somewhat more potent than flurazepam.
OriginatorSchiapparelli (Italy)
DefinitionChEBI: Doxefazepam is a benzodiazepine.
Brand nameDOXANS
Doxefazepam Preparation Products And Raw materials
7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo-1,4-diazepin-2-one monohydrochloride 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one 3-HYDROXY-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE Fludiazepam N-desalkylflurazepam OXAZEPAM DIETHANOL-O-TOLUIDINE Doxefazepam TEMAZEPAM
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