2-Chloro-5-nitropyridine

2-Chloro-5-nitropyridine Basic information

Product Name:	2-Chloro-5-nitropyridine
Synonyms:	2-Chloro-5-nitropyridine;3-Nitro-6-chloropyridine;2-Chloro-5-nitropyridine, 99% 25GR;5-Nitro-2-chloropyridine;6-Chloro-3-nitropyridine;2-Chloro-5-nitropyridine, 97+%;Chloro-5-nitropyrid;2-chloro-5-nitro-pyridin
CAS:	4548-45-2
MF:	C5H3ClN2O2
MW:	158.54
EINECS:	224-908-3
Product Categories:	alkyl chloride \|nitro-compound;Chlorinated heterocyclic series;Chloropyridines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;blocks;Pyridines;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Halides;Pyridines derivates;Heterocyclic Building Blocks;compounds of pyridine;Pyridine;1;bc0001
Mol File:	4548-45-2.mol

2-Chloro-5-nitropyridine Chemical Properties

Melting point	105-108 °C (lit.)
Boiling point	256.6±20.0 °C(Predicted)
density	1.6616 (rough estimate)
refractive index	1.5500 (estimate)
Fp	158°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-4.22±0.10(Predicted)
form	Crystalline Powder
color	Light yellow to beige
Water Solubility	Solubility in hot methanol. Insoluble in water.
BRN	120453
InChIKey	BAZVFQBTJPBRTJ-UHFFFAOYSA-N
CAS DataBase Reference	4548-45-2(CAS DataBase Reference)
NIST Chemistry Reference	2-Chloro-5-nitropyridine(4548-45-2)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
RTECS	US7175000
HazardClass	IRRITANT
HS Code	29333990

MSDS Information

Provider	Language
2-Chloro-5-nitropyridine	English

2-Chloro-5-nitropyridine Usage And Synthesis

Chemical Properties	white to light yellow crystal
Uses	2-Chloro-5-nitropyridine is used as a pharmaceutical intermediate.
Purification Methods	It crystallises from benzene or benzene/pet ether. [Beilstein 20/5 V 452.]

2-Chloro-5-nitropyridine Preparation Products And Raw materials

Raw materials

Nitric acid-->Phosphorus oxychloride-->2-Aminopyridine-->2-Hydroxy-5-nitropyridine-->2-Amino-5-nitropyridine-->2-Amino-6-chloro-3-nitropyridine-->2-Chloro-5-nitropyridin-4-amine

Preparation Products

5-Amino-2-methylpyridine-->5-AMINO-2-METHOXY-ISONICOTINIC ACID-->7-CHLORO-10-(4-HYDROXYANILINO)-2-METHOXY BENZO(B)-1,5-NAPHTHY RIDINE-->5-Aminopyridine-2-carboxylic Acid-->5-Amino-2-methoxypyridine-->5-Nitropyridine-2-carboxylic acid-->2-Methoxy-5-nitropyridine-->1-(5-aminopyridin-2-yl)piperidin-4-ol-->3-Amino-6-morpholinopyridine-->5-Amino-2-chloropyridine-->6-(1-PYRROLIDINYL)-3-PYRIDINAMINE-->3-Aminopyridine-->1-[5-NITROPYRIDIN-2-YL]PIPERIDINE-4-OL-->4-(5-Nitropyridin-2-yl)morpholine-->5-NITRO-2-(1-PYRROLIDINYL)PYRIDINE-->2-Chloro-5-nitropyridin-4-amine-->NVP-LDE225-->2-Methyl-5-nitropyridine

6-Chloro-2-methyl-3-nitropyridine 2,4-DICHLORO-5-NITROPYRIDINE 4-Chloronitrobenzene NITROGEN DIOXIDE 2-Chloro-3-cyanopyridine 2-CHLORO-4,6-DIMETHYL-5-NITRO-NICOTINONITRILE 2-Chloro-5-chloromethylpyridine 2-CHLORO-5-NITRO-6-(3-NITROPHENYL)-4-(TRIFLUOROMETHYL)NICOTINONITRILE 2-Nitrochlorobenzene Pentachloropyridine Difluorochloromethane 2-CHLORO-6-METHYL-5-NITRO-4-(TRIFLUOROMETHYL)NICOTINONITRILE Clopidol 2-Chloro-3-methyl-5-nitropyridine 3-Nitrochlorobenzene 2-Chloro-5-nitropyridine 2-Chloro-5-methylpyridine 4-Nitrobenzyl chloride

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